<p>We set <i>m</i><sub>I<sub>1</sub></sub> = 5 and <i>Δm</i> = 5 in all figures. The I, II and III differ in the value of <i>s</i> (=0.5, 1.0, 1.5). (a) MA, (b) PA, (c) MCS.</p
<p>The infectious (PFU/mL) and total (RNA/mL) viral load (top), and the fraction of infectious cells...
<p>Here α is fixed to 0.05 and linear mortality parameter <i>η</i> to 1.0. Linear infectivity respon...
Figure replicates Fig 3D and 3G from the main text, here under assumptions of complete tolerance. Pa...
<p>We set <i>m</i><sub>I<sub>1</sub></sub> = 5 and <i>s</i> = 1.5 in all figures. The I, II and III ...
<p>We set <i>m</i><sub>I<sub>1</sub></sub> = 5 and <i>Δm</i> = 5 in all figures. The I, II and III d...
<p>The left, center and right panels show the result in simulation by MA, PA and MCS, respectively. ...
Left: a model with host population structure (five assortatively mixing host groups) with increasing...
Starting from common assumptions, we build a rate equation model for multi-strain dis-ease dynamics ...
<p>Other parameters have the baseline values in <a href="http://www.plosone.org/article/info:doi/10....
<p>The contours show the mean set-point virus load in the population-level equilibrium. The heavy bl...
<p>The value of <i>γ</i><sub>0</sub> corresponds to the maximal proliferation rate in optimal condit...
Illustration of how host population (panel A) and strain (panel B) structure maintain coexistence by...
<p>A. Growth curves of the engineered strains and the WT strain in YNBD, B. Growth curves of the eng...
We analysed and simulated a two-strain Susceptible-Infected-Recovered (SIR) disease model with varyi...
<p>Viral loads of the virulent strain (strain 1; blue), and of the less virulent strain (strain 2; r...
<p>The infectious (PFU/mL) and total (RNA/mL) viral load (top), and the fraction of infectious cells...
<p>Here α is fixed to 0.05 and linear mortality parameter <i>η</i> to 1.0. Linear infectivity respon...
Figure replicates Fig 3D and 3G from the main text, here under assumptions of complete tolerance. Pa...
<p>We set <i>m</i><sub>I<sub>1</sub></sub> = 5 and <i>s</i> = 1.5 in all figures. The I, II and III ...
<p>We set <i>m</i><sub>I<sub>1</sub></sub> = 5 and <i>Δm</i> = 5 in all figures. The I, II and III d...
<p>The left, center and right panels show the result in simulation by MA, PA and MCS, respectively. ...
Left: a model with host population structure (five assortatively mixing host groups) with increasing...
Starting from common assumptions, we build a rate equation model for multi-strain dis-ease dynamics ...
<p>Other parameters have the baseline values in <a href="http://www.plosone.org/article/info:doi/10....
<p>The contours show the mean set-point virus load in the population-level equilibrium. The heavy bl...
<p>The value of <i>γ</i><sub>0</sub> corresponds to the maximal proliferation rate in optimal condit...
Illustration of how host population (panel A) and strain (panel B) structure maintain coexistence by...
<p>A. Growth curves of the engineered strains and the WT strain in YNBD, B. Growth curves of the eng...
We analysed and simulated a two-strain Susceptible-Infected-Recovered (SIR) disease model with varyi...
<p>Viral loads of the virulent strain (strain 1; blue), and of the less virulent strain (strain 2; r...
<p>The infectious (PFU/mL) and total (RNA/mL) viral load (top), and the fraction of infectious cells...
<p>Here α is fixed to 0.05 and linear mortality parameter <i>η</i> to 1.0. Linear infectivity respon...
Figure replicates Fig 3D and 3G from the main text, here under assumptions of complete tolerance. Pa...
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