Additional file 5: of Accumulation of amyloid-β by astrocytes result in enlarged endosomes and microvesicle-induced apoptosis of neurons

Additional file 5: of Adiponectin suppresses amyloid-β oligomer (AβO)-induced inflammatory response of microglia via AdipoR1-AMPK-NF-κB signaling pathway

Min Jian (394957)
Jason Kwan (164198)
Myriam Bunting (6739025)
Roy Ng (3539159)
Koon Chan (3539165)

May 2019

APN deficiency increased the amyloid plaque size and decreased microglia clustering around amyloid d...

Additional file 1: of α1-antitrypsin mitigates NLRP3-inflammasome activation in amyloid β1–42-stimulated murine astrocytes

Taraneh Ebrahimi (5799689)
Marcus Rust (5799692)
Sarah Kaiser (5799695)
Alexander Slowik (5799698)
Cordian Beyer (2733838)
Andreas Koczulla (3555509)
Jörg Schulz (4018502)
Pardes Habib (5799701)
Jan Bach (5799704)

September 2018

Figure S2. Cell counting revealed 95.2% astrocytes and 4.5% microglia. Approximately 0.4% of the cel...

Additional file 1: Figure S1. of Spinal cord injury induces astroglial conversion towards neuronal lineage

Harun Noristani (3467963)
Jean Sabourin (3467966)
Hassan Boukhaddaoui (202916)
Emilie Chan-Seng (3467969)
Yannick Gerber (3467960)
Florence Perrin (372628)

October 2016

Specific eGFP expression of astroglial cells in Aldh1l1-EGFP mice. Confocal micrographs showing astr...

Additional file 3: of Accumulation of amyloid-β by astrocytes result in enlarged endosomes and microvesicle-induced apoptosis of neurons

Sofia Söllvander (3402770)
Elisabeth Nikitidou (3402773)
Robin Brolin (3402767)
Linda Söderberg (3402776)
Dag Sehlin (333061)
Lars Lannfelt (333066)
Anna Erlandsson (175907)

May 2016

Intracellular localization of large Aβ42-555 inclusions in astrocytes. Intersections from a 3D z-sta...

Additional file 4: of Accumulation of amyloid-β by astrocytes result in enlarged endosomes and microvesicle-induced apoptosis of neurons

Sofia Söllvander (3402770)
Elisabeth Nikitidou (3402773)
Robin Brolin (3402767)
Linda Söderberg (3402776)
Dag Sehlin (333061)
Lars Lannfelt (333066)
Anna Erlandsson (175907)

May 2016

Immunostainings with Aβ42 specific antibodies confirm Aβ42 protofibril inclusions in astrocytes. Aft...

Additional file 12: of Accumulation of amyloid-β by astrocytes result in enlarged endosomes and microvesicle-induced apoptosis of neurons

Sofia Söllvander (3402770)
Elisabeth Nikitidou (3402773)
Robin Brolin (3402767)
Linda Söderberg (3402776)
Dag Sehlin (333061)
Lars Lannfelt (333066)
Anna Erlandsson (175907)

May 2016

Aβ42 protofibrils do not directly induce neuronal cell death. Cortical neurons were exposed to 0.1 μ...

Additional file 5: of The Aβ protofibril selective antibody mAb158 prevents accumulation of Aβ in astrocytes and rescues neurons from Aβ-induced cell death

Sofia Söllvander (3402770)
Elisabeth Nikitidou (3402773)
Linn Gallasch (5038016)
Marlena Zyśk (5038013)
Linda Söderberg (3402776)
Dag Sehlin (333061)
Lars Lannfelt (333066)
Anna Erlandsson (175907)

March 2018

Aβ42-555 protofibrils and mAb158 are engulfed and co-localize inside astrocytes. Time-lapse recordin...

Additional file 3: of The Aβ protofibril selective antibody mAb158 prevents accumulation of Aβ in astrocytes and rescues neurons from Aβ-induced cell death

Sofia Söllvander (3402770)
Elisabeth Nikitidou (3402773)
Linn Gallasch (5038016)
Marlena Zyśk (5038013)
Linda Söderberg (3402776)
Dag Sehlin (333061)
Lars Lannfelt (333066)
Anna Erlandsson (175907)

March 2018

The mAb1C3 lowers Aβ inclusions in astrocytes. Aβ42 protofibrils were accumulated in astrocytes (A),...

Additional file 5: of Glial cells are functionally impaired in juvenile neuronal ceroid lipofuscinosis and detrimental to neurons

Lotta Parviainen (4520035)
Sybille Dihanich (4520032)
Greg Anderson (2703046)
Andrew Wong (256256)
Helen Brooks (397642)
Rosella Abeti (460301)
Payam Rezaie (89114)
Giovanna Lalli (481271)
Simon Pope (4520038)
Simon Heales (49272)
Hannah Mitchison (4520041)
Brenda Williams (3565124)
Jonathan Cooper (222828)

October 2017

Table S1. Protein secretion profile of WT and Cln3 −/− astrocytes under basal conditions. Difference...

Additional file 6: of The Aβ protofibril selective antibody mAb158 prevents accumulation of Aβ in astrocytes and rescues neurons from Aβ-induced cell death

Sofia Söllvander (3402770)
Elisabeth Nikitidou (3402773)
Linn Gallasch (5038016)
Marlena Zyśk (5038013)
Linda Söderberg (3402776)
Dag Sehlin (333061)
Lars Lannfelt (333066)
Anna Erlandsson (175907)

March 2018

RmAb158 reduces Aβ inclusions in astrocytes. Co-cultures were exposed to Aβ42 protofibrils (A) or Aβ...

Additional file 4: of The Aβ protofibril selective antibody mAb158 prevents accumulation of Aβ in astrocytes and rescues neurons from Aβ-induced cell death

Sofia Söllvander (3402770)
Elisabeth Nikitidou (3402773)
Linn Gallasch (5038016)
Marlena Zyśk (5038013)
Linda Söderberg (3402776)
Dag Sehlin (333061)
Lars Lannfelt (333066)
Anna Erlandsson (175907)

March 2018

The irrelevant antibody MOPC-173 has a significantly lower effect on Aβ accumulation in astrocytes t...

Additional file 1: of Replication of multiple system atrophy prions in primary astrocyte cultures from transgenic mice expressing human α-synuclein

Zuzana Krejciova (4605781)
George Carlson (4605790)
Kurt Giles (195746)
Stanley Prusiner (4605775)

May 2019

Figure S1. Isolation and characterization of astrocyte cultures from transgenic (Tg) mice. Figure S2...

Additional file 1: of Mesencephalic astrocyte-derived neurotrophic factor (MANF) protects against Aβ toxicity via attenuating Aβ-induced endoplasmic reticulum stress

Shengchun Xu (5060504)
Zemin Di (6332741)
Yufeng He (5673119)
Runjie Wang (6332744)
Yuyang Ma (3695131)
Rui Sun (177521)
Jing Li (10611)
Tao Wang (12008)
Yujun Shen (3412115)
Shengyun Fang (207485)
Lijie Feng (3412118)
Yuxian Shen (454391)

February 2019

Figure S1. Aβ1–42 induces ER stress and upregulates MANF expression in primarily cultured rat neuron...

Additional file 2: of Mesencephalic astrocyte-derived neurotrophic factor (MANF) protects against Aβ toxicity via attenuating Aβ-induced endoplasmic reticulum stress

Shengchun Xu (5060504)
Zemin Di (6332741)
Yufeng He (5673119)
Runjie Wang (6332744)
Yuyang Ma (3695131)
Rui Sun (177521)
Jing Li (10611)
Tao Wang (12008)
Yujun Shen (3412115)
Shengyun Fang (207485)
Lijie Feng (3412118)
Yuxian Shen (454391)

February 2019

Figure S2. Representative images of Aβ deposition in the brains of APP/PS1 transgenic mice. Immunohi...

Additional file 1: Figure S1. of Astroglia acquires a toxic neuroinflammatory role in response to the cerebrospinal fluid from amyotrophic lateral sclerosis patients

Pooja-Shree Mishra (3501329)
Dinesh Dhull (3501338)
A. Nalini (3501335)
K. Vijayalakshmi (2015191)
T. Sathyaprabha (3501323)
Phalguni Alladi (3501326)
Trichur Raju (3501332)

August 2016

Representative phase contrast (a, câe) and confocal images of the enriched astroglial cultures (b,...

Additional file 5: of Adiponectin suppresses amyloid-β oligomer (AβO)-induced inflammatory response of microglia via AdipoR1-AMPK-NF-κB signaling pathway

Min Jian (394957)
Jason Kwan (164198)
Myriam Bunting (6739025)
Roy Ng (3539159)
Koon Chan (3539165)

May 2019

APN deficiency increased the amyloid plaque size and decreased microglia clustering around amyloid d...

Additional file 1: of α1-antitrypsin mitigates NLRP3-inflammasome activation in amyloid β1–42-stimulated murine astrocytes

Taraneh Ebrahimi (5799689)
Marcus Rust (5799692)
Sarah Kaiser (5799695)
Alexander Slowik (5799698)
Cordian Beyer (2733838)
Andreas Koczulla (3555509)
Jörg Schulz (4018502)
Pardes Habib (5799701)
Jan Bach (5799704)

September 2018

Figure S2. Cell counting revealed 95.2% astrocytes and 4.5% microglia. Approximately 0.4% of the cel...

Additional file 1: Figure S1. of Spinal cord injury induces astroglial conversion towards neuronal lineage

Harun Noristani (3467963)
Jean Sabourin (3467966)
Hassan Boukhaddaoui (202916)
Emilie Chan-Seng (3467969)
Yannick Gerber (3467960)
Florence Perrin (372628)

October 2016

Specific eGFP expression of astroglial cells in Aldh1l1-EGFP mice. Confocal micrographs showing astr...

Additional file 3: of Accumulation of amyloid-β by astrocytes result in enlarged endosomes and microvesicle-induced apoptosis of neurons

Sofia Söllvander (3402770)
Elisabeth Nikitidou (3402773)
Robin Brolin (3402767)
Linda Söderberg (3402776)
Dag Sehlin (333061)
Lars Lannfelt (333066)
Anna Erlandsson (175907)

May 2016

Intracellular localization of large Aβ42-555 inclusions in astrocytes. Intersections from a 3D z-sta...

Additional file 4: of Accumulation of amyloid-β by astrocytes result in enlarged endosomes and microvesicle-induced apoptosis of neurons

Sofia Söllvander (3402770)
Elisabeth Nikitidou (3402773)
Robin Brolin (3402767)
Linda Söderberg (3402776)
Dag Sehlin (333061)
Lars Lannfelt (333066)
Anna Erlandsson (175907)

May 2016

Immunostainings with Aβ42 specific antibodies confirm Aβ42 protofibril inclusions in astrocytes. Aft...

Additional file 12: of Accumulation of amyloid-β by astrocytes result in enlarged endosomes and microvesicle-induced apoptosis of neurons

Sofia Söllvander (3402770)
Elisabeth Nikitidou (3402773)
Robin Brolin (3402767)
Linda Söderberg (3402776)
Dag Sehlin (333061)
Lars Lannfelt (333066)
Anna Erlandsson (175907)

May 2016

Aβ42 protofibrils do not directly induce neuronal cell death. Cortical neurons were exposed to 0.1 μ...

Additional file 5: of The Aβ protofibril selective antibody mAb158 prevents accumulation of Aβ in astrocytes and rescues neurons from Aβ-induced cell death

Sofia Söllvander (3402770)
Elisabeth Nikitidou (3402773)
Linn Gallasch (5038016)
Marlena Zyśk (5038013)
Linda Söderberg (3402776)
Dag Sehlin (333061)
Lars Lannfelt (333066)
Anna Erlandsson (175907)

March 2018

Aβ42-555 protofibrils and mAb158 are engulfed and co-localize inside astrocytes. Time-lapse recordin...

Additional file 3: of The Aβ protofibril selective antibody mAb158 prevents accumulation of Aβ in astrocytes and rescues neurons from Aβ-induced cell death

Sofia Söllvander (3402770)
Elisabeth Nikitidou (3402773)
Linn Gallasch (5038016)
Marlena Zyśk (5038013)
Linda Söderberg (3402776)
Dag Sehlin (333061)
Lars Lannfelt (333066)
Anna Erlandsson (175907)

March 2018

The mAb1C3 lowers Aβ inclusions in astrocytes. Aβ42 protofibrils were accumulated in astrocytes (A),...

Additional file 5: of Glial cells are functionally impaired in juvenile neuronal ceroid lipofuscinosis and detrimental to neurons

Lotta Parviainen (4520035)
Sybille Dihanich (4520032)
Greg Anderson (2703046)
Andrew Wong (256256)
Helen Brooks (397642)
Rosella Abeti (460301)
Payam Rezaie (89114)
Giovanna Lalli (481271)
Simon Pope (4520038)
Simon Heales (49272)
Hannah Mitchison (4520041)
Brenda Williams (3565124)
Jonathan Cooper (222828)

October 2017

Table S1. Protein secretion profile of WT and Cln3 −/− astrocytes under basal conditions. Difference...

Additional file 6: of The Aβ protofibril selective antibody mAb158 prevents accumulation of Aβ in astrocytes and rescues neurons from Aβ-induced cell death

Sofia Söllvander (3402770)
Elisabeth Nikitidou (3402773)
Linn Gallasch (5038016)
Marlena Zyśk (5038013)
Linda Söderberg (3402776)
Dag Sehlin (333061)
Lars Lannfelt (333066)
Anna Erlandsson (175907)

March 2018

RmAb158 reduces Aβ inclusions in astrocytes. Co-cultures were exposed to Aβ42 protofibrils (A) or Aβ...

Additional file 4: of The Aβ protofibril selective antibody mAb158 prevents accumulation of Aβ in astrocytes and rescues neurons from Aβ-induced cell death

Sofia Söllvander (3402770)
Elisabeth Nikitidou (3402773)
Linn Gallasch (5038016)
Marlena Zyśk (5038013)
Linda Söderberg (3402776)
Dag Sehlin (333061)
Lars Lannfelt (333066)
Anna Erlandsson (175907)

March 2018

The irrelevant antibody MOPC-173 has a significantly lower effect on Aβ accumulation in astrocytes t...

Additional file 1: of Replication of multiple system atrophy prions in primary astrocyte cultures from transgenic mice expressing human α-synuclein

Zuzana Krejciova (4605781)
George Carlson (4605790)
Kurt Giles (195746)
Stanley Prusiner (4605775)

May 2019

Figure S1. Isolation and characterization of astrocyte cultures from transgenic (Tg) mice. Figure S2...

Additional file 1: of Mesencephalic astrocyte-derived neurotrophic factor (MANF) protects against Aβ toxicity via attenuating Aβ-induced endoplasmic reticulum stress

Shengchun Xu (5060504)
Zemin Di (6332741)
Yufeng He (5673119)
Runjie Wang (6332744)
Yuyang Ma (3695131)
Rui Sun (177521)
Jing Li (10611)
Tao Wang (12008)
Yujun Shen (3412115)
Shengyun Fang (207485)
Lijie Feng (3412118)
Yuxian Shen (454391)

February 2019

Figure S1. Aβ1–42 induces ER stress and upregulates MANF expression in primarily cultured rat neuron...

Additional file 2: of Mesencephalic astrocyte-derived neurotrophic factor (MANF) protects against Aβ toxicity via attenuating Aβ-induced endoplasmic reticulum stress

Shengchun Xu (5060504)
Zemin Di (6332741)
Yufeng He (5673119)
Runjie Wang (6332744)
Yuyang Ma (3695131)
Rui Sun (177521)
Jing Li (10611)
Tao Wang (12008)
Yujun Shen (3412115)
Shengyun Fang (207485)
Lijie Feng (3412118)
Yuxian Shen (454391)

February 2019

Figure S2. Representative images of Aβ deposition in the brains of APP/PS1 transgenic mice. Immunohi...

Additional file 1: Figure S1. of Astroglia acquires a toxic neuroinflammatory role in response to the cerebrospinal fluid from amyotrophic lateral sclerosis patients

Pooja-Shree Mishra (3501329)
Dinesh Dhull (3501338)
A. Nalini (3501335)
K. Vijayalakshmi (2015191)
T. Sathyaprabha (3501323)
Phalguni Alladi (3501326)
Trichur Raju (3501332)

August 2016

Representative phase contrast (a, câe) and confocal images of the enriched astroglial cultures (b,...

Additional file 5: of Adiponectin suppresses amyloid-β oligomer (AβO)-induced inflammatory response of microglia via AdipoR1-AMPK-NF-κB signaling pathway

Min Jian (394957)
Jason Kwan (164198)
Myriam Bunting (6739025)
Roy Ng (3539159)
Koon Chan (3539165)

May 2019

APN deficiency increased the amyloid plaque size and decreased microglia clustering around amyloid d...

Additional file 1: of α1-antitrypsin mitigates NLRP3-inflammasome activation in amyloid β1–42-stimulated murine astrocytes

Taraneh Ebrahimi (5799689)
Marcus Rust (5799692)
Sarah Kaiser (5799695)
Alexander Slowik (5799698)
Cordian Beyer (2733838)
Andreas Koczulla (3555509)
Jörg Schulz (4018502)
Pardes Habib (5799701)
Jan Bach (5799704)

September 2018

Figure S2. Cell counting revealed 95.2% astrocytes and 4.5% microglia. Approximately 0.4% of the cel...

Additional file 1: Figure S1. of Spinal cord injury induces astroglial conversion towards neuronal lineage

Harun Noristani (3467963)
Jean Sabourin (3467966)
Hassan Boukhaddaoui (202916)
Emilie Chan-Seng (3467969)
Yannick Gerber (3467960)
Florence Perrin (372628)

October 2016

Specific eGFP expression of astroglial cells in Aldh1l1-EGFP mice. Confocal micrographs showing astr...

Additional file 5: of Accumulation of amyloid-β by astrocytes result in enlarged endosomes and microvesicle-induced apoptosis of neurons

Abstract

Extracted data

Additional file 5: of Accumulation of amyloid-β by astrocytes result in enlarged endosomes and microvesicle-induced apoptosis of neurons

Abstract

Extracted data

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