Effects of P-FA, I-FA, and R-FA on the cytosolic expression of p-JNK, JNK, p-ERK1/2, ERK1/2, p-p38 MAPK, p38 MAPK, p-Akt, and Akt in the cortical penumbra.

<p>(A) Representative Western blot images show cytosolic p-JNK, JNK, p-ERK1/2, ERK1/2, p-p38 MAPK, p38 MAPK, p-Akt, and Akt expression in the cortical penumbra in the Sham, Vehicle, B-FA, P-FA, I-FA, R-FA, and D-FA groups 7 d after reperfusion. The ratios of (B) p-JNK/JNK, (C) p-ERK/ERK, (D) p-p38 MAPK/p38 MAPK, and (E) p-Akt/Akt expression were calculated in the cortical penumbra in the Sham, Vehicle, B-FA, P-FA, I-FA, R-FA, and D-FA groups (n = 5). cyto, cytosolic fraction. Data are presented as mean ± SD. *<i>P</i> < 0.05 versus the Sham group; #<i>P</i> < 0.05 versus the Vehicle group.