<p>Results were expressed as mean ± 95% confidence intervals of 12 independent experiments performed with chondrocytes isolated from 12 different patients. **p-value<0.01, ***p-value<0.001. (a) MMP-13 = matrix metalloproteinase-13, (b) BMP-2 = bone morphogenetic protein-2, ND = non detectable.</p
Purpose—To link MMP-13 activity and ECM remodeling to alterations in regulatory factors leading to a...
<p>Results were expressed as mean ± 95% confidence intervals of 12 independent experiments performed...
<p>Following transfection with siRNA, either non-targeting siCon (white bars) or one specific for <i...
<p><b>A.</b> Human MMP-13 mRNA expression in T/C-28a2 chondrocytes incubated with SERPINE2 (0.4 ng/m...
Chondrocytes isolated from normal adult cartilage were stimulated with 10 ng/mL recombinant IL-7 and...
<p>Primary human chondrocytes were incubated with AGEs (1 to 100 μg/ml). The expression of IL-1α, IL...
During development, mRNA for matrix metalloproteinase-13 (MMP-13) is found associated with cartilage...
<p>*P<0.05 and ***P<0.001 vs siC- transfected cells; <sup>###</sup> P<0.001 vs siC- plus IL-1α-stimu...
Human chondrocytes were treated with IL-1 (0.05 ng/mL) in combination with OSM (10 ng/mL) for the in...
Summary Objective Matrix metalloproteinase-13 (MMP-13) is an extracellular MMP that cleaves type II ...
Osteoarthritis (OA) is a chronic disease of the joints and bones due to trauma or other joint-relate...
<p>A: mRNA expression; B: protein production. MMP-13 was detected in chondrocytes (cells and culture...
<p>Immunohistochemical staining of MMP-13 in frontal sections of knee joint. (A) Typical staining of...
SummaryObjectiveMatrix metalloproteinase-13 (MMP-13) is an extracellular MMP that cleaves type II co...
Human chondrocytes were treated with IL-1 (0.05 ng/mL) in combination with OSM (10 ng/mL) for the in...
Purpose—To link MMP-13 activity and ECM remodeling to alterations in regulatory factors leading to a...
<p>Results were expressed as mean ± 95% confidence intervals of 12 independent experiments performed...
<p>Following transfection with siRNA, either non-targeting siCon (white bars) or one specific for <i...
<p><b>A.</b> Human MMP-13 mRNA expression in T/C-28a2 chondrocytes incubated with SERPINE2 (0.4 ng/m...
Chondrocytes isolated from normal adult cartilage were stimulated with 10 ng/mL recombinant IL-7 and...
<p>Primary human chondrocytes were incubated with AGEs (1 to 100 μg/ml). The expression of IL-1α, IL...
During development, mRNA for matrix metalloproteinase-13 (MMP-13) is found associated with cartilage...
<p>*P<0.05 and ***P<0.001 vs siC- transfected cells; <sup>###</sup> P<0.001 vs siC- plus IL-1α-stimu...
Human chondrocytes were treated with IL-1 (0.05 ng/mL) in combination with OSM (10 ng/mL) for the in...
Summary Objective Matrix metalloproteinase-13 (MMP-13) is an extracellular MMP that cleaves type II ...
Osteoarthritis (OA) is a chronic disease of the joints and bones due to trauma or other joint-relate...
<p>A: mRNA expression; B: protein production. MMP-13 was detected in chondrocytes (cells and culture...
<p>Immunohistochemical staining of MMP-13 in frontal sections of knee joint. (A) Typical staining of...
SummaryObjectiveMatrix metalloproteinase-13 (MMP-13) is an extracellular MMP that cleaves type II co...
Human chondrocytes were treated with IL-1 (0.05 ng/mL) in combination with OSM (10 ng/mL) for the in...
Purpose—To link MMP-13 activity and ECM remodeling to alterations in regulatory factors leading to a...
<p>Results were expressed as mean ± 95% confidence intervals of 12 independent experiments performed...
<p>Following transfection with siRNA, either non-targeting siCon (white bars) or one specific for <i...