Additional file 6: Figure S4. of Altered excitatory-inhibitory balance within somatosensory cortex is associated with enhanced plasticity and pain sensitivity in a mouse model of multiple sclerosis

S1 IHC in pre-symptomatic and clinical onset EAE: absence of cortical-infiltrating CD3+ and/or CD45+ T cells. A) Representative fluorescence photomicrographs of CD3+ staining in S1 from control (CFA) and EAE animals at the pre-symptomatic stage (7–9 dpi PRE) or clinical onset (ONS). No infiltrating T cells were apparent. B) Representative fluorescence photomicrographs of CD45+ staining in S1 from control (CFA) and EAE animals at the pre-symptomatic stage (7–9 dpi PRE) or clinical onset (ONS). No infiltrating T cells were apparent. (PDF 1663 kb