Transcriptome profiles of macrophage-like cells in BC tumors.

<p>(<b>a</b>) Results of principal component analysis (PCA) for the subset of 1238 genes up- or downregulated in at least one comparison between MMTV-PyMT and BC-PyMT, HBCx-5, -24 or -34. The 15 samples, triplicates of MMTV-PyMT (green), BC-PyMT (orange), HBCx-5 (red), HBCx-24 (yellow) and HBCx-34 (blue), were projected oton the first three principal components, which accounted for ~58% of the total variability. Hierarchical clustering of the genes from the (<b>b</b>) “Immune system process” or (<b>c</b>) “Metabolic process” pathways from Gene Ontology analysis identified as significantly up- or downregulated in at least one comparison between BC-PyMT and HBCx-5, -24 and -34.