Additional file 1 of Computing energy landscape maps and structural excursions of proteins

Visualization in 2D of Map and Paths Computed for H-Ras G12S. The computed map for the H-Ras G12S variant is projected onto 2D and projections are color-coded by Rosetta score12 energy values. Low-cost paths (costs in REUs are listed) modeling the On →Off structural excursion are also drawn. The projections of experimentally-known structures on the top two PCs are related by showing whether the structures are captured in the wet laboratory for the WT or variants. (PDF 1597 kb