<p><b>Comparison of the C domain opening with the breaking of the strongest hydrogen bonds in (A) IGF-I and (B) IGF-II</b>.</p
AbstractWe have characterized a large-scale inactive-to-active conformational change in the activati...
Insulin receptor is a multi-domain signalling protein acting as a dimer. It comprises an extracellul...
More effective production of human insulin is important, because insulin is the main medication that...
<p><b>Strongest hydrogen bonds between the upper flank of the C loop and its lower flank and/or A do...
<p><b>Temporal correlation between the core and C domain openings in (A) IGF-I and (B) IGF-II.</b> T...
<p><b>Illustration of the distances of the C</b><sub><b>α</b></sub><b>atoms used in describing the c...
<div><p>The insulin-family proteins bind to their own receptors, but insulin-like growth factor II (...
The insulin-family proteins bind to their own receptors, but insulin-like growth factor II (IGF-II) ...
<p><b>Distribution of the distance representing the C domain opening in (A) IGF-I and (B) IGF-II.</b...
<p><b>Convergence analysis of the PMF calculation over the simulation time in (A) IGF-I and (B) IGF-...
Diabetes is one of the top causes of death, with the number of people diagnosed constantly increasin...
A sequence of complex conformational changes is required for insulin to bind to the insulin receptor...
A sequence of complex conformational changes is required for insulin to bind to the insulin receptor...
Synergistic interactions among peptides and receptors of the insulin family are required for glucose...
Synergistic interactions among peptides and receptors of the insulin family are required for glucose...
AbstractWe have characterized a large-scale inactive-to-active conformational change in the activati...
Insulin receptor is a multi-domain signalling protein acting as a dimer. It comprises an extracellul...
More effective production of human insulin is important, because insulin is the main medication that...
<p><b>Strongest hydrogen bonds between the upper flank of the C loop and its lower flank and/or A do...
<p><b>Temporal correlation between the core and C domain openings in (A) IGF-I and (B) IGF-II.</b> T...
<p><b>Illustration of the distances of the C</b><sub><b>α</b></sub><b>atoms used in describing the c...
<div><p>The insulin-family proteins bind to their own receptors, but insulin-like growth factor II (...
The insulin-family proteins bind to their own receptors, but insulin-like growth factor II (IGF-II) ...
<p><b>Distribution of the distance representing the C domain opening in (A) IGF-I and (B) IGF-II.</b...
<p><b>Convergence analysis of the PMF calculation over the simulation time in (A) IGF-I and (B) IGF-...
Diabetes is one of the top causes of death, with the number of people diagnosed constantly increasin...
A sequence of complex conformational changes is required for insulin to bind to the insulin receptor...
A sequence of complex conformational changes is required for insulin to bind to the insulin receptor...
Synergistic interactions among peptides and receptors of the insulin family are required for glucose...
Synergistic interactions among peptides and receptors of the insulin family are required for glucose...
AbstractWe have characterized a large-scale inactive-to-active conformational change in the activati...
Insulin receptor is a multi-domain signalling protein acting as a dimer. It comprises an extracellul...
More effective production of human insulin is important, because insulin is the main medication that...