Reduction of the recruitment of M2 macrophages in wound granulation tissues in EP3 and EP4 receptor knockout mice.

<p>(A, B) The left panels show representative images of CD11b (green) and IL-1β (red) or MR (red) in the granulation tissues of WT and <i>EP3</i>^{<i>–/–</i>}(A) or <i>EP4</i>^{<i>–/–</i>}(B) mice on day 3. Scale bars: 10 μm. The data are quantified in the right panel. Data are expressed as the mean ± SEM (n = 6). ***P < 0.001.