Additional file 1: of Targeted high-throughput sequencing of candidate genes for chronic obstructive pulmonary disease

Additional file 1: of Lung function reductions associated with motor vehicle density in chronic obstructive pulmonary disease: a cross-sectional study

Monika Nitschke (3457571)
Sarah Appleton (3457565)
Qiaoyu Li (3457568)
Graeme Tucker (402091)
Pushan Shah (2173612)
Peng Bi (424140)
Dino Pisaniello (785064)
Robert Adams (77677)

October 2016

Lung function reductions associated with motor vehicle density in chronic obstructive pulmonary dise...

Additional file 1 of Association between the oxidative stress gene polymorphism and chronic obstructive pulmonary disease risk: a meta-analysis

Ting Zhou (38572)
Qiunan Zuo (8979401)
Mengchun Chen (15193175)
Yingying Zhao (349236)
Xiaohui Li (73588)
Shujin Guo (4344310)

October 2023

Additional file 1: Supplementary Table 1. The characteristics of the eligible studies. Supplementary...

Additional file 1: of Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis

Zhu, Zhaozhong
Wang, Xiaofang
Li, Xihao
Lin, Yifei
Shen, Sipeng
Liu, Cong-Lin
Hobbs, Brain D.
Hasegawa, Kohei
Liang, Liming
Boezen, H. Marike
Camargo, Carlos A.
Cho, Michael H.
Christiani, David C.
University of Groningen
Life Course Epidemiology (LCE)
Groningen Research Institute for Asthma and COPD (GRIAC)
Harvard School of Public Health
Zhengzhou University
Harvard Medical School
Massachusetts General Hospital
Arctic Centre, Univ. of Groningen

January 2019

Table S1. Summary of GWAS data. Table S2. SNP based heritability and genomic inflation factor estima...

Additional file 5: of Targeted high-throughput sequencing of candidate genes for chronic obstructive pulmonary disease

Hans Matsson (217735)
Cilla Söderhäll (117617)
Elisabet Einarsdottir (359261)
Maxime Lamontagne (116448)
Sanna Gudmundsson (3499502)
Helena Backman (3499499)
Anne Lindberg (3442631)
Eva Rönmark (764539)
Juha Kere (11900)
Don Sin (128552)
Dirkje Postma (3410420)
Yohan Bossé (69571)
Bo Lundbäck (154245)
Joakim Klar (549023)

November 2016

Pairwise linkage disequilibrium (LD) of associated variants. A list of detected genetic variants fou...

Additional file 4: of Targeted high-throughput sequencing of candidate genes for chronic obstructive pulmonary disease

Hans Matsson (217735)
Cilla Söderhäll (117617)
Elisabet Einarsdottir (359261)
Maxime Lamontagne (116448)
Sanna Gudmundsson (3499502)
Helena Backman (3499499)
Anne Lindberg (3442631)
Eva Rönmark (764539)
Juha Kere (11900)
Don Sin (128552)
Dirkje Postma (3410420)
Yohan Bossé (69571)
Bo Lundbäck (154245)
Joakim Klar (549023)

November 2016

Gene burden analysis of common variants. The table present the SKAT analysis of gene burden of commo...

Additional file 7 of Targeted high-throughput sequencing of candidate genes for chronic obstructive pulmonary disease

Hans Matsson (217735)
Cilla Söderhäll (117617)
Elisabet Einarsdottir (359261)
Maxime Lamontagne (116448)
Sanna Gudmundsson (3499502)
Helena Backman (3499499)
Anne Lindberg (3442631)
Eva Rönmark (764539)
Juha Kere (11900)
Don Sin (128552)
Dirkje Postma (3410420)
Yohan Bossé (69571)
Bo Lundbäck (154245)
Joakim Klar (549023)

November 2016

Probe sets replicated in both replication sets (UBC and Groningen) in the lung eQTL analyses. A tabl...

Additional file 4: of Whole exome sequencing identifies novel candidate genes that modify chronic obstructive pulmonary disease susceptibility

Shannon Bruse (3481571)
Michael Moreau (3481577)
Yana Bromberg (51423)
Jun-Ho Jang (748271)
Nan Wang (21935)
Hongseok Ha (3400535)
Maria Picchi (3481559)
Yong Lin (177139)
Raymond Langley (3481580)
Clifford Qualls (117765)
Julia Klensney-Tait (3481565)
Joseph Zabner (138271)
Shuguang Leng (173462)
Jenny Mao (3481568)
Steven Belinsky (3481562)
Jinchuan Xing (11012)
Toru Nyunoya (3481574)

January 2016

siRNA screening in vitro analysis for 81 COPD candidate genes. For the 81 candidate genes, the detai...

Additional file 1: of Whole exome sequencing identifies novel candidate genes that modify chronic obstructive pulmonary disease susceptibility

Shannon Bruse (3481571)
Michael Moreau (3481577)
Yana Bromberg (51423)
Jun-Ho Jang (748271)
Nan Wang (21935)
Hongseok Ha (3400535)
Maria Picchi (3481559)
Yong Lin (177139)
Raymond Langley (3481580)
Clifford Qualls (117765)
Julia Klensney-Tait (3481565)
Joseph Zabner (138271)
Shuguang Leng (173462)
Jenny Mao (3481568)
Steven Belinsky (3481562)
Jinchuan Xing (11012)
Toru Nyunoya (3481574)

January 2016

COPD candidate genes prioritized by the VAAST analysis. Results from different VAAST run settings (T...

Additional file 5: of Whole exome sequencing identifies novel candidate genes that modify chronic obstructive pulmonary disease susceptibility

Shannon Bruse (3481571)
Michael Moreau (3481577)
Yana Bromberg (51423)
Jun-Ho Jang (748271)
Nan Wang (21935)
Hongseok Ha (3400535)
Maria Picchi (3481559)
Yong Lin (177139)
Raymond Langley (3481580)
Clifford Qualls (117765)
Julia Klensney-Tait (3481565)
Joseph Zabner (138271)
Shuguang Leng (173462)
Jenny Mao (3481568)
Steven Belinsky (3481562)
Jinchuan Xing (11012)
Toru Nyunoya (3481574)

January 2016

Annotated variants for the 81 COPD candidate genes. Whole exome sequencing variants identified in th...

Additional file 2: of RNA-sequencing across three matched tissues reveals shared and tissue-specific gene expression and pathway signatures of COPD

Jarrett Morrow (662723)
Robert Chase (1436653)
Margaret Parker (3457517)
Kimberly Glass (416881)
Minseok Seo (316795)
Miguel Divo (2621386)
Caroline Owen (6548522)
Peter Castaldi (2993694)
Dawn DeMeo (3115695)
Edwin Silverman (758792)
Craig Hersh (3457529)

April 2019

Supplemental Methods. Additional detail regarding the methods in this study. (PDF 56 kb

Additional file 3: of Whole exome sequencing identifies novel candidate genes that modify chronic obstructive pulmonary disease susceptibility

Shannon Bruse (3481571)
Michael Moreau (3481577)
Yana Bromberg (51423)
Jun-Ho Jang (748271)
Nan Wang (21935)
Hongseok Ha (3400535)
Maria Picchi (3481559)
Yong Lin (177139)
Raymond Langley (3481580)
Clifford Qualls (117765)
Julia Klensney-Tait (3481565)
Joseph Zabner (138271)
Shuguang Leng (173462)
Jenny Mao (3481568)
Steven Belinsky (3481562)
Jinchuan Xing (11012)
Toru Nyunoya (3481574)

January 2016

The abundance of gene expression in primary human epithelial cell cultures using RNA-Seq. Expression...

Additional file 1: of RNAseq analysis of bronchial epithelial cells to identify COPD-associated genes and SNPs

Jiyoun Yeo (448396)
Diego Morales (760820)
Tian Chen (550371)
Erin Crawford (3995537)
Xiaolu Zhang (433873)
Thomas Blomquist (3995534)
Albert Levin (483979)
Pierre Massion (4913062)
Douglas Arenberg (4913056)
David Midthun (4622974)
Peter Mazzone (4031270)
Steven Nathan (4913053)
Ronald Wainz (4913068)
Patrick Nana-Sinkam (425104)
Paige Willey (4913065)
Taylor Arend (4913074)
Karanbir Padda (4913077)
Shuhao Qiu (4070320)
Alexei Federov (4913071)
Dawn-Alita Hernandez (71925)
Jeffrey Hammersley (4913080)
Youngsook Yoon (71926)
Fadi Safi (4913059)
Sadik Khuder (86473)
James Willey (3995531)

March 2018

Tables S1, S2, S3, S4, S5 and S6. Table S1. This table provides: a) Gene-specific assay information ...

Additional file 1: of RNA-sequencing across three matched tissues reveals shared and tissue-specific gene expression and pathway signatures of COPD

Jarrett Morrow (662723)
Robert Chase (1436653)
Margaret Parker (3457517)
Kimberly Glass (416881)
Minseok Seo (316795)
Miguel Divo (2621386)
Caroline Owen (6548522)
Peter Castaldi (2993694)
Dawn DeMeo (3115695)
Edwin Silverman (758792)
Craig Hersh (3457529)

April 2019

Supplemental Figures: Additional figures to support the findings of this study. (PDF 780 kb

Additional file 3: of Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis

Zhaozhong Zhu (551360)
Xiaofang Wang (163746)
Xihao Li (6548387)
Yifei Lin (6197672)
Sipeng Shen (4391278)
Cong-Lin Liu (3123927)
Brain Hobbs (6548393)
Kohei Hasegawa (3467948)
Liming Liang (69800)
H. Boezen (3410438)
Carlos Camargo (3451940)
Michael Cho (562027)
David Christiani (72443)

April 2019

Figure S1. QQ plot of resting heart rate. Figure S2. QQ plot of high blood pressure. Figure S3. Gene...

Additional file 3: of RNA-sequencing across three matched tissues reveals shared and tissue-specific gene expression and pathway signatures of COPD

Jarrett Morrow (662723)
Robert Chase (1436653)
Margaret Parker (3457517)
Kimberly Glass (416881)
Minseok Seo (316795)
Miguel Divo (2621386)
Caroline Owen (6548522)
Peter Castaldi (2993694)
Dawn DeMeo (3115695)
Edwin Silverman (758792)
Craig Hersh (3457529)

April 2019

Supplemental Tables: Additional tables to support the findings of this study. Table S4. Differential...

Additional file 1: of Lung function reductions associated with motor vehicle density in chronic obstructive pulmonary disease: a cross-sectional study

Monika Nitschke (3457571)
Sarah Appleton (3457565)
Qiaoyu Li (3457568)
Graeme Tucker (402091)
Pushan Shah (2173612)
Peng Bi (424140)
Dino Pisaniello (785064)
Robert Adams (77677)

October 2016

Lung function reductions associated with motor vehicle density in chronic obstructive pulmonary dise...

Additional file 1 of Association between the oxidative stress gene polymorphism and chronic obstructive pulmonary disease risk: a meta-analysis

Ting Zhou (38572)
Qiunan Zuo (8979401)
Mengchun Chen (15193175)
Yingying Zhao (349236)
Xiaohui Li (73588)
Shujin Guo (4344310)

October 2023

Additional file 1: Supplementary Table 1. The characteristics of the eligible studies. Supplementary...

Additional file 1: of Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis

Zhu, Zhaozhong
Wang, Xiaofang
Li, Xihao
Lin, Yifei
Shen, Sipeng
Liu, Cong-Lin
Hobbs, Brain D.
Hasegawa, Kohei
Liang, Liming
Boezen, H. Marike
Camargo, Carlos A.
Cho, Michael H.
Christiani, David C.
University of Groningen
Life Course Epidemiology (LCE)
Groningen Research Institute for Asthma and COPD (GRIAC)
Harvard School of Public Health
Zhengzhou University
Harvard Medical School
Massachusetts General Hospital
Arctic Centre, Univ. of Groningen

January 2019

Table S1. Summary of GWAS data. Table S2. SNP based heritability and genomic inflation factor estima...

Additional file 5: of Targeted high-throughput sequencing of candidate genes for chronic obstructive pulmonary disease

Hans Matsson (217735)
Cilla Söderhäll (117617)
Elisabet Einarsdottir (359261)
Maxime Lamontagne (116448)
Sanna Gudmundsson (3499502)
Helena Backman (3499499)
Anne Lindberg (3442631)
Eva Rönmark (764539)
Juha Kere (11900)
Don Sin (128552)
Dirkje Postma (3410420)
Yohan Bossé (69571)
Bo Lundbäck (154245)
Joakim Klar (549023)

November 2016

Pairwise linkage disequilibrium (LD) of associated variants. A list of detected genetic variants fou...

Additional file 4: of Targeted high-throughput sequencing of candidate genes for chronic obstructive pulmonary disease

Hans Matsson (217735)
Cilla Söderhäll (117617)
Elisabet Einarsdottir (359261)
Maxime Lamontagne (116448)
Sanna Gudmundsson (3499502)
Helena Backman (3499499)
Anne Lindberg (3442631)
Eva Rönmark (764539)
Juha Kere (11900)
Don Sin (128552)
Dirkje Postma (3410420)
Yohan Bossé (69571)
Bo Lundbäck (154245)
Joakim Klar (549023)

November 2016

Gene burden analysis of common variants. The table present the SKAT analysis of gene burden of commo...

Additional file 7 of Targeted high-throughput sequencing of candidate genes for chronic obstructive pulmonary disease

Hans Matsson (217735)
Cilla Söderhäll (117617)
Elisabet Einarsdottir (359261)
Maxime Lamontagne (116448)
Sanna Gudmundsson (3499502)
Helena Backman (3499499)
Anne Lindberg (3442631)
Eva Rönmark (764539)
Juha Kere (11900)
Don Sin (128552)
Dirkje Postma (3410420)
Yohan Bossé (69571)
Bo Lundbäck (154245)
Joakim Klar (549023)

November 2016

Probe sets replicated in both replication sets (UBC and Groningen) in the lung eQTL analyses. A tabl...

Additional file 4: of Whole exome sequencing identifies novel candidate genes that modify chronic obstructive pulmonary disease susceptibility

Shannon Bruse (3481571)
Michael Moreau (3481577)
Yana Bromberg (51423)
Jun-Ho Jang (748271)
Nan Wang (21935)
Hongseok Ha (3400535)
Maria Picchi (3481559)
Yong Lin (177139)
Raymond Langley (3481580)
Clifford Qualls (117765)
Julia Klensney-Tait (3481565)
Joseph Zabner (138271)
Shuguang Leng (173462)
Jenny Mao (3481568)
Steven Belinsky (3481562)
Jinchuan Xing (11012)
Toru Nyunoya (3481574)

January 2016

siRNA screening in vitro analysis for 81 COPD candidate genes. For the 81 candidate genes, the detai...

Additional file 1: of Whole exome sequencing identifies novel candidate genes that modify chronic obstructive pulmonary disease susceptibility

Shannon Bruse (3481571)
Michael Moreau (3481577)
Yana Bromberg (51423)
Jun-Ho Jang (748271)
Nan Wang (21935)
Hongseok Ha (3400535)
Maria Picchi (3481559)
Yong Lin (177139)
Raymond Langley (3481580)
Clifford Qualls (117765)
Julia Klensney-Tait (3481565)
Joseph Zabner (138271)
Shuguang Leng (173462)
Jenny Mao (3481568)
Steven Belinsky (3481562)
Jinchuan Xing (11012)
Toru Nyunoya (3481574)

January 2016

COPD candidate genes prioritized by the VAAST analysis. Results from different VAAST run settings (T...

Additional file 5: of Whole exome sequencing identifies novel candidate genes that modify chronic obstructive pulmonary disease susceptibility

Shannon Bruse (3481571)
Michael Moreau (3481577)
Yana Bromberg (51423)
Jun-Ho Jang (748271)
Nan Wang (21935)
Hongseok Ha (3400535)
Maria Picchi (3481559)
Yong Lin (177139)
Raymond Langley (3481580)
Clifford Qualls (117765)
Julia Klensney-Tait (3481565)
Joseph Zabner (138271)
Shuguang Leng (173462)
Jenny Mao (3481568)
Steven Belinsky (3481562)
Jinchuan Xing (11012)
Toru Nyunoya (3481574)

January 2016

Annotated variants for the 81 COPD candidate genes. Whole exome sequencing variants identified in th...

Additional file 2: of RNA-sequencing across three matched tissues reveals shared and tissue-specific gene expression and pathway signatures of COPD

Jarrett Morrow (662723)
Robert Chase (1436653)
Margaret Parker (3457517)
Kimberly Glass (416881)
Minseok Seo (316795)
Miguel Divo (2621386)
Caroline Owen (6548522)
Peter Castaldi (2993694)
Dawn DeMeo (3115695)
Edwin Silverman (758792)
Craig Hersh (3457529)

April 2019

Supplemental Methods. Additional detail regarding the methods in this study. (PDF 56 kb

Additional file 3: of Whole exome sequencing identifies novel candidate genes that modify chronic obstructive pulmonary disease susceptibility

Shannon Bruse (3481571)
Michael Moreau (3481577)
Yana Bromberg (51423)
Jun-Ho Jang (748271)
Nan Wang (21935)
Hongseok Ha (3400535)
Maria Picchi (3481559)
Yong Lin (177139)
Raymond Langley (3481580)
Clifford Qualls (117765)
Julia Klensney-Tait (3481565)
Joseph Zabner (138271)
Shuguang Leng (173462)
Jenny Mao (3481568)
Steven Belinsky (3481562)
Jinchuan Xing (11012)
Toru Nyunoya (3481574)

January 2016

The abundance of gene expression in primary human epithelial cell cultures using RNA-Seq. Expression...

Additional file 1: of RNAseq analysis of bronchial epithelial cells to identify COPD-associated genes and SNPs

Jiyoun Yeo (448396)
Diego Morales (760820)
Tian Chen (550371)
Erin Crawford (3995537)
Xiaolu Zhang (433873)
Thomas Blomquist (3995534)
Albert Levin (483979)
Pierre Massion (4913062)
Douglas Arenberg (4913056)
David Midthun (4622974)
Peter Mazzone (4031270)
Steven Nathan (4913053)
Ronald Wainz (4913068)
Patrick Nana-Sinkam (425104)
Paige Willey (4913065)
Taylor Arend (4913074)
Karanbir Padda (4913077)
Shuhao Qiu (4070320)
Alexei Federov (4913071)
Dawn-Alita Hernandez (71925)
Jeffrey Hammersley (4913080)
Youngsook Yoon (71926)
Fadi Safi (4913059)
Sadik Khuder (86473)
James Willey (3995531)

March 2018

Tables S1, S2, S3, S4, S5 and S6. Table S1. This table provides: a) Gene-specific assay information ...

Additional file 1: of RNA-sequencing across three matched tissues reveals shared and tissue-specific gene expression and pathway signatures of COPD

Jarrett Morrow (662723)
Robert Chase (1436653)
Margaret Parker (3457517)
Kimberly Glass (416881)
Minseok Seo (316795)
Miguel Divo (2621386)
Caroline Owen (6548522)
Peter Castaldi (2993694)
Dawn DeMeo (3115695)
Edwin Silverman (758792)
Craig Hersh (3457529)

April 2019

Supplemental Figures: Additional figures to support the findings of this study. (PDF 780 kb

Additional file 3: of Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis

Zhaozhong Zhu (551360)
Xiaofang Wang (163746)
Xihao Li (6548387)
Yifei Lin (6197672)
Sipeng Shen (4391278)
Cong-Lin Liu (3123927)
Brain Hobbs (6548393)
Kohei Hasegawa (3467948)
Liming Liang (69800)
H. Boezen (3410438)
Carlos Camargo (3451940)
Michael Cho (562027)
David Christiani (72443)

April 2019

Figure S1. QQ plot of resting heart rate. Figure S2. QQ plot of high blood pressure. Figure S3. Gene...

Additional file 3: of RNA-sequencing across three matched tissues reveals shared and tissue-specific gene expression and pathway signatures of COPD

Jarrett Morrow (662723)
Robert Chase (1436653)
Margaret Parker (3457517)
Kimberly Glass (416881)
Minseok Seo (316795)
Miguel Divo (2621386)
Caroline Owen (6548522)
Peter Castaldi (2993694)
Dawn DeMeo (3115695)
Edwin Silverman (758792)
Craig Hersh (3457529)

April 2019

Supplemental Tables: Additional tables to support the findings of this study. Table S4. Differential...

Additional file 1: of Lung function reductions associated with motor vehicle density in chronic obstructive pulmonary disease: a cross-sectional study

Monika Nitschke (3457571)
Sarah Appleton (3457565)
Qiaoyu Li (3457568)
Graeme Tucker (402091)
Pushan Shah (2173612)
Peng Bi (424140)
Dino Pisaniello (785064)
Robert Adams (77677)

October 2016

Lung function reductions associated with motor vehicle density in chronic obstructive pulmonary dise...

Additional file 1 of Association between the oxidative stress gene polymorphism and chronic obstructive pulmonary disease risk: a meta-analysis

Ting Zhou (38572)
Qiunan Zuo (8979401)
Mengchun Chen (15193175)
Yingying Zhao (349236)
Xiaohui Li (73588)
Shujin Guo (4344310)

October 2023

Additional file 1: Supplementary Table 1. The characteristics of the eligible studies. Supplementary...

Additional file 1: of Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis

Zhu, Zhaozhong
Wang, Xiaofang
Li, Xihao
Lin, Yifei
Shen, Sipeng
Liu, Cong-Lin
Hobbs, Brain D.
Hasegawa, Kohei
Liang, Liming
Boezen, H. Marike
Camargo, Carlos A.
Cho, Michael H.
Christiani, David C.
University of Groningen
Life Course Epidemiology (LCE)
Groningen Research Institute for Asthma and COPD (GRIAC)
Harvard School of Public Health
Zhengzhou University
Harvard Medical School
Massachusetts General Hospital
Arctic Centre, Univ. of Groningen

January 2019

Table S1. Summary of GWAS data. Table S2. SNP based heritability and genomic inflation factor estima...

Additional file 1: of Targeted high-throughput sequencing of candidate genes for chronic obstructive pulmonary disease

Abstract

Extracted data

Additional file 1: of Targeted high-throughput sequencing of candidate genes for chronic obstructive pulmonary disease

Abstract

Extracted data

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