Instantaneous iCore moieties.

<p>Carbon and phosphate containing moieties in an extreme pathway of the <i>E. coli</i> core network that corresponds to glycolysis. Four conserved moieties are distinguished by shape in the figure. The pathway also conserves one oxygen atom moiety and two hydrogen atom moieties that were omitted to simplify the figure. Metabolite abbreviations are, Glc: D-glucose (VMH [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004999#pcbi.1004999.ref023" target="_blank">23</a>] ID: glc_D), PEP: phosphoenolpyruvate (VMH ID: pep), Pyr: pyruvate (VMH ID: pyr), F6P: D-fructose 6-phosphate (VMH ID: f6p), ATP: adenosine triphosphate (VMH ID: atp), ADP: adenosine diphosphate (VMH ID: adp), FDP: D-fructose 1,6-bisphosphate (VMH ID: fdp), DHAP: dihydroxyacetone phosphate (VMH ID: dhap), G3P: glyceraldehyde 3-phosphate (VHM ID: g3p), NAD: nicotinamide adenine dinucleotide (VMH ID: nad), P_<i>bluei</i>: orthophosphate (VMH ID: pi), NADH: reduced nicotinamide adenine dinucleotide (VMH ID: nadh), DPG: 1,3-bisphospho-D-glycerate (VMH ID: 13dpg), Lac: D-lactate (VMH ID: lac_D). The glucose moiety (circles) is transitive whereas the other three moieties are internal, including the phosphate moiety (squares) which was classified as integrative in the full iCore network.