Body weight changes following fasting and refeeding.

<p>Adaptation to isolation measured by body weight gain in floxed and <i>muscle IL-6 KO</i> male (n = 13/12) and female (n = 14/14) mice (<b>A</b>). Female mice recovered somewhat faster but no effects of genotype were obvious. Following this period of acclimatization, the mice were subjected to fasting overnight and then food was allowed (refeeding) (<b>B, C</b>). Body weight changes following fasting and at 4, 24 and 48h after refeeding (<b>B</b>) and food intake at 1, 2, 3, 4, 24, and 48h after refeeding (<b>C</b>) are shown. The effect of muscle IL-6 deficiency was significant only for food intake and in some of the refeeding periods in female mice. ★ <i>p</i> at least < 0.05 <i>versus</i> floxed mice.