Additional file 5: Figure S3. of Evolutionary acquisition of promoter-associated non-coding RNA (pancRNA) repertoires diversifies species-dependent gene activation mechanisms in mammals

Histone modification across the regions around TSSs of each tissue-specific gene. RPM (Read count per million mapped reads) derived from ChIP-seq data (H3K4me1, H3K4me3, and H3K27ac) of mouse cerebral cortex (Cortex), cerebellum (Cbellum), heart, kidney, and liver across the regions around TSSs (−2,000 bp to +2,000 bp relative to TSS). In this analysis, each tissue-specific gene, each pancRNA-partnered tissue-specific gene, and each pancRNA-lacking tissue-specific gene was utilized (TSI > 0.9). The standard error of the mean across the regions is shown as semi-transparent shading around the mean curve. (A) Cerebellum-specific genes. (B) Heart-specific genes. (C) Kidney-specific genes. (D) Liver-specific genes. (PDF 617 kb