Additional file 2: Figure S2. of Thioredoxin-interacting protein links endoplasmic reticulum stress to inflammatory brain injury and apoptosis after subarachnoid haemorrhage

The TXNIP and inflammatory factor expression after TXNIP siRNA treatment. Representative Western blot of TXNIP, TRX1, NLRP3, cleaved Caspase-1 (CC1) and cleaved IL-1β (a). Densitometric quantification of protein band optical densities for TRX1, CC1 and cleaved IL-1β (b-d). TXNIP and inflammatory factor expression were reduced by TXNIP siRNA treatment. Analysed by Fusion (fx 7 Spectra, Vilber, France). Results were expressed as a percentage of the values of β-actin. *p < 0.05 vs. sham; @p < 0.05 vs SAH+ control siRNA. (EPS 1213 kb