Chromosome distribution of the MPNST vs. NF gene signature.

<p>The gene signature distribution was calculated from the 336 genes with positive score <b>(a)</b>, and from the 243 genes with negative score <b>(b)</b>. Bar diagrams compare the observed distribution of MPNST vs. NF gene percentage in the human chromosome arms (dark bars) with the expected distribution according to the human ENSEMBL database (light bars). Statistical significance of the gene signature over-represented chromosome arms is above the bars. Over-represented human chromosome bands in the MPNST vs. NF gene signature are shown below each chart. Their statistical significance is shown at the top right side of band names. (****) P(X≥x) < 0.0001, (***) 0.0001< P(X≥x) < 0.001, (**) 0.001< P(X≥x) < 0.01, (*) 0.01< P(X≥x) < 0.05.