<p>In comparison to untreated control significant enhancement of ATP-production was observed in all cell lines. No difference was detectable between non-neoplastic mammary gland derived cell line MTH53A and neoplastic tissue derived cell lines. Data are shown as mean ± SD, n≥3 and are presented as relative ATP-production (mitochondrial respiration) in comparison to untreated control (%). Control was set to 100%. Statistical analysis was performed with two-tailed t-test, *p<0.05, **p<0.01, ***p<0.001.</p
<p>(A) Intracellular ATP levels in cells treated for 48 h with different concentrations of 2-DG. Dat...
<p>Exponentially growing MDA-MB-231 and MCF-7 cells were treated with DMSO (control) or 500 nmol/L o...
<p>(A) Comparison of glucose uptake in MCF10A, MCF-7 and MDA-MB-231 cells. Glucose uptake was determ...
<p>(A) OCR (using MitoXpress), (B) extracellular lactate production, (C) pyruvate kinase activity, (...
<p>Data was assessed with Luminex Magnetic Bead technology. PDH-P at Ser<sup>232</sup> decreased sig...
<p>hPTECs showed a decreased ATP content 6h after treatment that was not affected by rescuing amino ...
<p>The Na,K-ATPase activity in total membranes isolated from non-tumorous 184D, 184A, and MCF10A (10...
A slight decrease in ATP levels was found at 1 and 24 h while remaining constant at 4 h in cells exp...
<p>(A, B) ATP content of uPAR<sup>+</sup> cells and uPAR<sup>-</sup> cells treated with 2-DG, oligom...
<p>Average ATP-stimulated Ca<sup>2+</sup> entry response (100 µM ATP), store-operated Ca<sup>2+</sup...
<p>Kinetic of intracellular and extracellular released ATP was performed by ELISA (A) and luciferin-...
<p>(A) Cell viability was determined as described above. 20 mmol/L DCA treatment decreased viability...
<p>The L02 cells were treated with various doses (25, 50, 75, or 100 µM) of GCDCA for 6 h. The resul...
<p>(A) ROUTINE, LEAK and ETS respiration rates measured in HeLa cells transfected with DmHsp22 (blue...
MCF-7 cells were seeded at a density of 1x 105 cells/well in 12-well plates and grown as described a...
<p>(A) Intracellular ATP levels in cells treated for 48 h with different concentrations of 2-DG. Dat...
<p>Exponentially growing MDA-MB-231 and MCF-7 cells were treated with DMSO (control) or 500 nmol/L o...
<p>(A) Comparison of glucose uptake in MCF10A, MCF-7 and MDA-MB-231 cells. Glucose uptake was determ...
<p>(A) OCR (using MitoXpress), (B) extracellular lactate production, (C) pyruvate kinase activity, (...
<p>Data was assessed with Luminex Magnetic Bead technology. PDH-P at Ser<sup>232</sup> decreased sig...
<p>hPTECs showed a decreased ATP content 6h after treatment that was not affected by rescuing amino ...
<p>The Na,K-ATPase activity in total membranes isolated from non-tumorous 184D, 184A, and MCF10A (10...
A slight decrease in ATP levels was found at 1 and 24 h while remaining constant at 4 h in cells exp...
<p>(A, B) ATP content of uPAR<sup>+</sup> cells and uPAR<sup>-</sup> cells treated with 2-DG, oligom...
<p>Average ATP-stimulated Ca<sup>2+</sup> entry response (100 µM ATP), store-operated Ca<sup>2+</sup...
<p>Kinetic of intracellular and extracellular released ATP was performed by ELISA (A) and luciferin-...
<p>(A) Cell viability was determined as described above. 20 mmol/L DCA treatment decreased viability...
<p>The L02 cells were treated with various doses (25, 50, 75, or 100 µM) of GCDCA for 6 h. The resul...
<p>(A) ROUTINE, LEAK and ETS respiration rates measured in HeLa cells transfected with DmHsp22 (blue...
MCF-7 cells were seeded at a density of 1x 105 cells/well in 12-well plates and grown as described a...
<p>(A) Intracellular ATP levels in cells treated for 48 h with different concentrations of 2-DG. Dat...
<p>Exponentially growing MDA-MB-231 and MCF-7 cells were treated with DMSO (control) or 500 nmol/L o...
<p>(A) Comparison of glucose uptake in MCF10A, MCF-7 and MDA-MB-231 cells. Glucose uptake was determ...