Additional file 6: Figure S5. of Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment

Additional file 6: of The pro- and anti-tumor roles of mesenchymal stem cells toward BRCA1-IRIS-overexpressing TNBC cells

Daniel Ryan (97944)
Bibbin Paul (3819457)
Jim Koziol (6627149)
Wael ElShamy (6627152)

April 2019

Figure S6. IRIS-silencing converts TNBC phenotype into luminal phenotype in breast cancer cells. The...

Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment

Minako Sakurai
Yasuhiro Miki
Kiyoshi Takagi
Takashi Suzuki
Takanori Ishida
Noriaki Ohuchi
Hironobu Sasano

June 2017

Abstract Background Breast adipocytes play important roles in both the development and function of m...

Additional file 2: of Adipocyte-derived IL-6 and leptin promote breast Cancer metastasis via upregulation of Lysyl Hydroxylase-2 expression

Jin-Yong He (6100892)
Xiao-Hui Wei (6100895)
Si-Jing Li (6100898)
Yang Liu (4829)
Hao-Lin Hu (6100901)
Zheng-Zheng Li (1637104)
Xin-Hong Kuang (6100904)
Lai Wang (23747)
Xin Shi (139139)
Sheng-Tao Yuan (6100907)
Li Sun (4624)

December 2018

Figure S1. Collagen and PLOD2 expression were significantly increased following coculture with adipo...

Additional file 4: Figure S3. of Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment

Minako Sakurai (4126699)
Yasuhiro Miki (368958)
Kiyoshi Takagi (4126696)
Takashi Suzuki (8491)
Takanori Ishida (822205)
Noriaki Ohuchi (360735)
Hironobu Sasano (368960)

June 2017

Detection of strong S100A7 expressions at the invasive front of MCF7 by interaction with ASCs, showi...

Additional file 1: of Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment

Minako Sakurai (4126699)
Yasuhiro Miki (368958)
Kiyoshi Takagi (4126696)
Takashi Suzuki (8491)
Takanori Ishida (822205)
Noriaki Ohuchi (360735)
Hironobu Sasano (368960)

June 2017

Supplementary information with materials and methods for supplementary figures, legends of Figures S...

Additional file 7: Figure S6. of Upregulation of EGFR signaling is correlated with tumor stroma remodeling and tumor recurrence in FGFR1-driven breast cancer

Xue Holdman (3581840)
Thomas Welte (421622)
Kimal Rajapakshe (543871)
Adam Pond (3581837)
Cristian Coarfa (114538)
Qianxing Mo (169134)
Shixia Huang (11609)
Susan Hilsenbeck (765988)
Dean Edwards (3581834)
Xiang Zhang (19800)
Jeffrey Rosen (3172593)

November 2015

The number of S100A8-positive cells is positively correlated with the number of Gr1+CD11bhigh cells....

Additional file 4: of Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP)

Camille Lehuédé (6241601)
Xia Li (14984)
Stéphanie Dauvillier (6241604)
Charlotte Vaysse (6241607)
Camille Franchet (6241610)
Emily Clement (6241613)
David Esteve (183184)
Mélanie Longué (6241616)
Léonor Chaltiel (6241619)
Sophie Gonidec (6241622)
Ikrame Lazar (6241625)
Aline Geneste (6241628)
Charles Dumontet (193436)
Philippe Valet (231001)
Laurence Nieto (8668)
Frédérique Fallone (6241631)
Catherine Muller (231004)

January 2019

Figure S2. Adipocyte soluble factors reproduce the effect of adipocyte-conditioned medium (AdCM) on ...

Additional file 5: Figure S4. of Enhanced metastatic capacity of breast cancer cells after interaction and hybrid formation with mesenchymal stroma/stem cells (MSC)

Catharina Melzer (4764342)
Juliane von der Ohe (4764339)
Ralf Hass (283575)

January 2018

Ki67 expression in MDA-hyb1 and MDA-hyb2 cells. Cell cultures of MDA-MB-231cherry, MDA-hyb1 and MDA-...

Additional file 6: of Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP)

Camille Lehuédé (6241601)
Xia Li (14984)
Stéphanie Dauvillier (6241604)
Charlotte Vaysse (6241607)
Camille Franchet (6241610)
Emily Clement (6241613)
David Esteve (183184)
Mélanie Longué (6241616)
Léonor Chaltiel (6241619)
Sophie Gonidec (6241622)
Ikrame Lazar (6241625)
Aline Geneste (6241628)
Charles Dumontet (193436)
Philippe Valet (231001)
Laurence Nieto (8668)
Frédérique Fallone (6241631)
Catherine Muller (231004)

January 2019

Figure S4. Validation of the two additional small interfering RNAs (siRNAs) targeting major vault pr...

Additional file 8: of Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP)

Camille Lehuédé (6241601)
Xia Li (14984)
Stéphanie Dauvillier (6241604)
Charlotte Vaysse (6241607)
Camille Franchet (6241610)
Emily Clement (6241613)
David Esteve (183184)
Mélanie Longué (6241616)
Léonor Chaltiel (6241619)
Sophie Gonidec (6241622)
Ikrame Lazar (6241625)
Aline Geneste (6241628)
Charles Dumontet (193436)
Philippe Valet (231001)
Laurence Nieto (8668)
Frédérique Fallone (6241631)
Catherine Muller (231004)

January 2019

Figure S6. Hematoxylin/eosin staining of the tumor used to represent major vault protein (MVP) expre...

Additional file 5: of Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers

Amy Strong (3505457)
Jason Ohlstein (659920)
Brandi Biagas (3575105)
Lyndsay Rhodes (3575099)
Dorothy Pei (3575102)
H. Tucker (3575108)
Claire Llamas (3575096)
Annie Bowles (3505478)
Maria Dutreil (3505475)
Shijia Zhang (497219)
Jeffrey Gimble (3505463)
Matthew Burow (3575111)
Bruce Bunnell (3505469)

August 2015

mRNA expression of T47D cells after exposure to leptin knockdown adipose stromal/stem cells (ASCs). ...

Additional file 2: of Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP)

Camille Lehuédé (6241601)
Xia Li (14984)
Stéphanie Dauvillier (6241604)
Charlotte Vaysse (6241607)
Camille Franchet (6241610)
Emily Clement (6241613)
David Esteve (183184)
Mélanie Longué (6241616)
Léonor Chaltiel (6241619)
Sophie Gonidec (6241622)
Ikrame Lazar (6241625)
Aline Geneste (6241628)
Charles Dumontet (193436)
Philippe Valet (231001)
Laurence Nieto (8668)
Frédérique Fallone (6241631)
Catherine Muller (231004)

January 2019

Table S1. Clinical characteristics of the patients with breast cancer and histopathological characte...

Additional file 4: of Utilization of adipocyte-derived lipids and enhanced intracellular trafficking of fatty acids contribute to breast cancer progression

Dejuan Yang (5414129)
Yunhai Li (513276)
Lei Xing (129950)
Yiqing Tan (5414135)
Jiazheng Sun (5414126)
Beilei Zeng (5414132)
Tingxiu Xiang (334805)
Jinxiang Tan (5414138)
Guosheng Ren (334816)
Yuanyuan Wang (20181)

June 2018

Figure S3. (A). Relative mRNA expression levels of FABP4, FABP5 and CD36 in breast cancer cell lines...

Additional file 4: of Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers

Amy Strong (3505457)
Jason Ohlstein (659920)
Brandi Biagas (3575105)
Lyndsay Rhodes (3575099)
Dorothy Pei (3575102)
H. Tucker (3575108)
Claire Llamas (3575096)
Annie Bowles (3505478)
Maria Dutreil (3505475)
Shijia Zhang (497219)
Jeffrey Gimble (3505463)
Matthew Burow (3575111)
Bruce Bunnell (3505469)

August 2015

mRNA expression of ZR75 cells after exposure to leptin knockdown adipose stromal/stem cells (ASCs). ...

Additional file 7: of Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP)

Camille Lehuédé (6241601)
Xia Li (14984)
Stéphanie Dauvillier (6241604)
Charlotte Vaysse (6241607)
Camille Franchet (6241610)
Emily Clement (6241613)
David Esteve (183184)
Mélanie Longué (6241616)
Léonor Chaltiel (6241619)
Sophie Gonidec (6241622)
Ikrame Lazar (6241625)
Aline Geneste (6241628)
Charles Dumontet (193436)
Philippe Valet (231001)
Laurence Nieto (8668)
Frédérique Fallone (6241631)
Catherine Muller (231004)

January 2019

Figure S5. Major vault protein (MVP) is implicated in doxorubicin (DOX) efflux and mediates adipocyt...

Additional file 6: of The pro- and anti-tumor roles of mesenchymal stem cells toward BRCA1-IRIS-overexpressing TNBC cells

Daniel Ryan (97944)
Bibbin Paul (3819457)
Jim Koziol (6627149)
Wael ElShamy (6627152)

April 2019

Figure S6. IRIS-silencing converts TNBC phenotype into luminal phenotype in breast cancer cells. The...

Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment

Minako Sakurai
Yasuhiro Miki
Kiyoshi Takagi
Takashi Suzuki
Takanori Ishida
Noriaki Ohuchi
Hironobu Sasano

June 2017

Abstract Background Breast adipocytes play important roles in both the development and function of m...

Additional file 2: of Adipocyte-derived IL-6 and leptin promote breast Cancer metastasis via upregulation of Lysyl Hydroxylase-2 expression

Jin-Yong He (6100892)
Xiao-Hui Wei (6100895)
Si-Jing Li (6100898)
Yang Liu (4829)
Hao-Lin Hu (6100901)
Zheng-Zheng Li (1637104)
Xin-Hong Kuang (6100904)
Lai Wang (23747)
Xin Shi (139139)
Sheng-Tao Yuan (6100907)
Li Sun (4624)

December 2018

Figure S1. Collagen and PLOD2 expression were significantly increased following coculture with adipo...

Additional file 4: Figure S3. of Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment

Minako Sakurai (4126699)
Yasuhiro Miki (368958)
Kiyoshi Takagi (4126696)
Takashi Suzuki (8491)
Takanori Ishida (822205)
Noriaki Ohuchi (360735)
Hironobu Sasano (368960)

June 2017

Detection of strong S100A7 expressions at the invasive front of MCF7 by interaction with ASCs, showi...

Additional file 1: of Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment

Minako Sakurai (4126699)
Yasuhiro Miki (368958)
Kiyoshi Takagi (4126696)
Takashi Suzuki (8491)
Takanori Ishida (822205)
Noriaki Ohuchi (360735)
Hironobu Sasano (368960)

June 2017

Supplementary information with materials and methods for supplementary figures, legends of Figures S...

Additional file 7: Figure S6. of Upregulation of EGFR signaling is correlated with tumor stroma remodeling and tumor recurrence in FGFR1-driven breast cancer

Xue Holdman (3581840)
Thomas Welte (421622)
Kimal Rajapakshe (543871)
Adam Pond (3581837)
Cristian Coarfa (114538)
Qianxing Mo (169134)
Shixia Huang (11609)
Susan Hilsenbeck (765988)
Dean Edwards (3581834)
Xiang Zhang (19800)
Jeffrey Rosen (3172593)

November 2015

The number of S100A8-positive cells is positively correlated with the number of Gr1+CD11bhigh cells....

Additional file 4: of Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP)

Camille Lehuédé (6241601)
Xia Li (14984)
Stéphanie Dauvillier (6241604)
Charlotte Vaysse (6241607)
Camille Franchet (6241610)
Emily Clement (6241613)
David Esteve (183184)
Mélanie Longué (6241616)
Léonor Chaltiel (6241619)
Sophie Gonidec (6241622)
Ikrame Lazar (6241625)
Aline Geneste (6241628)
Charles Dumontet (193436)
Philippe Valet (231001)
Laurence Nieto (8668)
Frédérique Fallone (6241631)
Catherine Muller (231004)

January 2019

Figure S2. Adipocyte soluble factors reproduce the effect of adipocyte-conditioned medium (AdCM) on ...

Additional file 5: Figure S4. of Enhanced metastatic capacity of breast cancer cells after interaction and hybrid formation with mesenchymal stroma/stem cells (MSC)

Catharina Melzer (4764342)
Juliane von der Ohe (4764339)
Ralf Hass (283575)

January 2018

Ki67 expression in MDA-hyb1 and MDA-hyb2 cells. Cell cultures of MDA-MB-231cherry, MDA-hyb1 and MDA-...

Additional file 6: of Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP)

Camille Lehuédé (6241601)
Xia Li (14984)
Stéphanie Dauvillier (6241604)
Charlotte Vaysse (6241607)
Camille Franchet (6241610)
Emily Clement (6241613)
David Esteve (183184)
Mélanie Longué (6241616)
Léonor Chaltiel (6241619)
Sophie Gonidec (6241622)
Ikrame Lazar (6241625)
Aline Geneste (6241628)
Charles Dumontet (193436)
Philippe Valet (231001)
Laurence Nieto (8668)
Frédérique Fallone (6241631)
Catherine Muller (231004)

January 2019

Figure S4. Validation of the two additional small interfering RNAs (siRNAs) targeting major vault pr...

Additional file 8: of Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP)

Camille Lehuédé (6241601)
Xia Li (14984)
Stéphanie Dauvillier (6241604)
Charlotte Vaysse (6241607)
Camille Franchet (6241610)
Emily Clement (6241613)
David Esteve (183184)
Mélanie Longué (6241616)
Léonor Chaltiel (6241619)
Sophie Gonidec (6241622)
Ikrame Lazar (6241625)
Aline Geneste (6241628)
Charles Dumontet (193436)
Philippe Valet (231001)
Laurence Nieto (8668)
Frédérique Fallone (6241631)
Catherine Muller (231004)

January 2019

Figure S6. Hematoxylin/eosin staining of the tumor used to represent major vault protein (MVP) expre...

Additional file 5: of Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers

Amy Strong (3505457)
Jason Ohlstein (659920)
Brandi Biagas (3575105)
Lyndsay Rhodes (3575099)
Dorothy Pei (3575102)
H. Tucker (3575108)
Claire Llamas (3575096)
Annie Bowles (3505478)
Maria Dutreil (3505475)
Shijia Zhang (497219)
Jeffrey Gimble (3505463)
Matthew Burow (3575111)
Bruce Bunnell (3505469)

August 2015

mRNA expression of T47D cells after exposure to leptin knockdown adipose stromal/stem cells (ASCs). ...

Additional file 2: of Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP)

Camille Lehuédé (6241601)
Xia Li (14984)
Stéphanie Dauvillier (6241604)
Charlotte Vaysse (6241607)
Camille Franchet (6241610)
Emily Clement (6241613)
David Esteve (183184)
Mélanie Longué (6241616)
Léonor Chaltiel (6241619)
Sophie Gonidec (6241622)
Ikrame Lazar (6241625)
Aline Geneste (6241628)
Charles Dumontet (193436)
Philippe Valet (231001)
Laurence Nieto (8668)
Frédérique Fallone (6241631)
Catherine Muller (231004)

January 2019

Table S1. Clinical characteristics of the patients with breast cancer and histopathological characte...

Additional file 4: of Utilization of adipocyte-derived lipids and enhanced intracellular trafficking of fatty acids contribute to breast cancer progression

Dejuan Yang (5414129)
Yunhai Li (513276)
Lei Xing (129950)
Yiqing Tan (5414135)
Jiazheng Sun (5414126)
Beilei Zeng (5414132)
Tingxiu Xiang (334805)
Jinxiang Tan (5414138)
Guosheng Ren (334816)
Yuanyuan Wang (20181)

June 2018

Figure S3. (A). Relative mRNA expression levels of FABP4, FABP5 and CD36 in breast cancer cell lines...

Additional file 4: of Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers

Amy Strong (3505457)
Jason Ohlstein (659920)
Brandi Biagas (3575105)
Lyndsay Rhodes (3575099)
Dorothy Pei (3575102)
H. Tucker (3575108)
Claire Llamas (3575096)
Annie Bowles (3505478)
Maria Dutreil (3505475)
Shijia Zhang (497219)
Jeffrey Gimble (3505463)
Matthew Burow (3575111)
Bruce Bunnell (3505469)

August 2015

mRNA expression of ZR75 cells after exposure to leptin knockdown adipose stromal/stem cells (ASCs). ...

Additional file 7: of Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP)

Camille Lehuédé (6241601)
Xia Li (14984)
Stéphanie Dauvillier (6241604)
Charlotte Vaysse (6241607)
Camille Franchet (6241610)
Emily Clement (6241613)
David Esteve (183184)
Mélanie Longué (6241616)
Léonor Chaltiel (6241619)
Sophie Gonidec (6241622)
Ikrame Lazar (6241625)
Aline Geneste (6241628)
Charles Dumontet (193436)
Philippe Valet (231001)
Laurence Nieto (8668)
Frédérique Fallone (6241631)
Catherine Muller (231004)

January 2019

Figure S5. Major vault protein (MVP) is implicated in doxorubicin (DOX) efflux and mediates adipocyt...

Additional file 6: of The pro- and anti-tumor roles of mesenchymal stem cells toward BRCA1-IRIS-overexpressing TNBC cells

Daniel Ryan (97944)
Bibbin Paul (3819457)
Jim Koziol (6627149)
Wael ElShamy (6627152)

April 2019

Figure S6. IRIS-silencing converts TNBC phenotype into luminal phenotype in breast cancer cells. The...

Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment

Minako Sakurai
Yasuhiro Miki
Kiyoshi Takagi
Takashi Suzuki
Takanori Ishida
Noriaki Ohuchi
Hironobu Sasano

June 2017

Abstract Background Breast adipocytes play important roles in both the development and function of m...

Additional file 2: of Adipocyte-derived IL-6 and leptin promote breast Cancer metastasis via upregulation of Lysyl Hydroxylase-2 expression

Jin-Yong He (6100892)
Xiao-Hui Wei (6100895)
Si-Jing Li (6100898)
Yang Liu (4829)
Hao-Lin Hu (6100901)
Zheng-Zheng Li (1637104)
Xin-Hong Kuang (6100904)
Lai Wang (23747)
Xin Shi (139139)
Sheng-Tao Yuan (6100907)
Li Sun (4624)

December 2018

Figure S1. Collagen and PLOD2 expression were significantly increased following coculture with adipo...

Additional file 6: Figure S5. of Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment

Abstract

Extracted data

Additional file 6: Figure S5. of Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment

Abstract

Extracted data

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