Additional file 1: of Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment

Minako Sakurai (4126699)
Yasuhiro Miki (368958)
Kiyoshi Takagi (4126696)
Takashi Suzuki (8491)
Takanori Ishida (822205)
Noriaki Ohuchi (360735)
Hironobu Sasano (368960)

Publication date

June 2017

DOI

10.6084/m9.figshare.c.3806539_d1.v1

Abstract

Supplementary information with materials and methods for supplementary figures, legends of Figures S1âS5, and Tables S1 and S2 listing primer and siRNA sequences used in this study. (DOCX 32 kb

Extracted data

We use cookies to provide a better user experience.

Data Protection

Additional file 1: of Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment

Minako Sakurai (4126699)
Yasuhiro Miki (368958)
Kiyoshi Takagi (4126696)
Takashi Suzuki (8491)
Takanori Ishida (822205)
Noriaki Ohuchi (360735)
Hironobu Sasano (368960)

Open link

Publication date

June 2017

DOI

10.6084/m9.figshare.c.3806539_d1.v1

Abstract

Supplementary information with materials and methods for supplementary figures, legends of Figures S1âS5, and Tables S1 and S2 listing primer and siRNA sequences used in this study. (DOCX 32 kb

Extracted data

Camille Lehuédé (6241601)
Xia Li (14984)
Stéphanie Dauvillier (6241604)
Charlotte Vaysse (6241607)
Camille Franchet (6241610)
Emily Clement (6241613)
David Esteve (183184)
Mélanie Longué (6241616)
Léonor Chaltiel (6241619)
Sophie Gonidec (6241622)
Ikrame Lazar (6241625)
Aline Geneste (6241628)
Charles Dumontet (193436)
Philippe Valet (231001)
Laurence Nieto (8668)
Frédérique Fallone (6241631)
Catherine Muller (231004)

January 2019

Figure S6. Hematoxylin/eosin staining of the tumor used to represent major vault protein (MVP) expre...

Additional file 7: of Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers

Amy Strong (3505457)
Jason Ohlstein (659920)
Brandi Biagas (3575105)
Lyndsay Rhodes (3575099)
Dorothy Pei (3575102)
H. Tucker (3575108)
Claire Llamas (3575096)
Annie Bowles (3505478)
Maria Dutreil (3505475)
Shijia Zhang (497219)
Jeffrey Gimble (3505463)
Matthew Burow (3575111)
Bruce Bunnell (3505469)

August 2015

Adipose stromal/stem (ASCs) cells isolated from obese women ( obASCs ) enhance metastasis of breast ...

Additional file 2: of RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3

Yi Niu (456782)
Ziyou Lin (6525587)
Arabella Wan (6525590)
Honglei Chen (125181)
Heng Liang (813618)
Lei Sun (45752)
Yuan Wang (14955)
Xi Li (19208)
Xiao-feng Xiong (5467394)
Bo Wei (188204)
Xiaobin Wu (6525596)
Guohui Wan (6525599)

March 2019

Figure S1. Gene expression in breast cancer. a Volcano plot of gene expression changes in the transc...

Additional file 4: Figure S3. of Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment

Minako Sakurai (4126699)
Yasuhiro Miki (368958)
Kiyoshi Takagi (4126696)
Takashi Suzuki (8491)
Takanori Ishida (822205)
Noriaki Ohuchi (360735)
Hironobu Sasano (368960)

June 2017

Detection of strong S100A7 expressions at the invasive front of MCF7 by interaction with ASCs, showi...

Additional file 6: Figure S5. of Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment

Minako Sakurai (4126699)
Yasuhiro Miki (368958)
Kiyoshi Takagi (4126696)
Takashi Suzuki (8491)
Takanori Ishida (822205)
Noriaki Ohuchi (360735)
Hironobu Sasano (368960)

June 2017

Web-based Kaplan-Meier analysis of S100A7 expression among patients with breast cancer, illustrating...

Additional file 1: of Adipocyte-derived IL-6 and leptin promote breast Cancer metastasis via upregulation of Lysyl Hydroxylase-2 expression

Jin-Yong He (6100892)
Xiao-Hui Wei (6100895)
Si-Jing Li (6100898)
Yang Liu (4829)
Hao-Lin Hu (6100901)
Zheng-Zheng Li (1637104)
Xin-Hong Kuang (6100904)
Lai Wang (23747)
Xin Shi (139139)
Sheng-Tao Yuan (6100907)
Li Sun (4624)

December 2018

Table S1. Sequences of the primers used to detect gene expression by qRT-PCR. Table S2. Characteriza...

Additional file 2: of Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP)

Camille Lehuédé (6241601)
Xia Li (14984)
Stéphanie Dauvillier (6241604)
Charlotte Vaysse (6241607)
Camille Franchet (6241610)
Emily Clement (6241613)
David Esteve (183184)
Mélanie Longué (6241616)
Léonor Chaltiel (6241619)
Sophie Gonidec (6241622)
Ikrame Lazar (6241625)
Aline Geneste (6241628)
Charles Dumontet (193436)
Philippe Valet (231001)
Laurence Nieto (8668)
Frédérique Fallone (6241631)
Catherine Muller (231004)

January 2019

Table S1. Clinical characteristics of the patients with breast cancer and histopathological characte...

Additional file 2: of Adipocyte-derived IL-6 and leptin promote breast Cancer metastasis via upregulation of Lysyl Hydroxylase-2 expression

Jin-Yong He (6100892)
Xiao-Hui Wei (6100895)
Si-Jing Li (6100898)
Yang Liu (4829)
Hao-Lin Hu (6100901)
Zheng-Zheng Li (1637104)
Xin-Hong Kuang (6100904)
Lai Wang (23747)
Xin Shi (139139)
Sheng-Tao Yuan (6100907)
Li Sun (4624)

December 2018

Figure S1. Collagen and PLOD2 expression were significantly increased following coculture with adipo...

Additional file 6: of Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP)

Camille Lehuédé (6241601)
Xia Li (14984)
Stéphanie Dauvillier (6241604)
Charlotte Vaysse (6241607)
Camille Franchet (6241610)
Emily Clement (6241613)
David Esteve (183184)
Mélanie Longué (6241616)
Léonor Chaltiel (6241619)
Sophie Gonidec (6241622)
Ikrame Lazar (6241625)
Aline Geneste (6241628)
Charles Dumontet (193436)
Philippe Valet (231001)
Laurence Nieto (8668)
Frédérique Fallone (6241631)
Catherine Muller (231004)

January 2019

Figure S4. Validation of the two additional small interfering RNAs (siRNAs) targeting major vault pr...

Additional file 1: of Leptin produced by obesity-altered adipose stem cells promotes metastasis but not tumorigenesis of triple-negative breast cancer in orthotopic xenograft and patient-derived xenograft models

Rachel Sabol (6438179)
Annie Bowles (3505478)
Alex Côté (6727181)
Rachel Wise (6727184)
Benjamen O’Donnell (6727187)
Margarite Matossian (6040496)
Fokhrul Hossain (6040487)
Hope Burks (6438176)
Luis Valle (6727190)
Lucio Miele (81383)
Bridgette Collins-Burow (444016)
Matthew Burow (3575111)
Bruce Bunnell (3505469)

May 2019

Figure S1. Secreted factors from adipose stem cells promotes proliferation and migration of breast c...

Additional file 4: of Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers

Amy Strong (3505457)
Jason Ohlstein (659920)
Brandi Biagas (3575105)
Lyndsay Rhodes (3575099)
Dorothy Pei (3575102)
H. Tucker (3575108)
Claire Llamas (3575096)
Annie Bowles (3505478)
Maria Dutreil (3505475)
Shijia Zhang (497219)
Jeffrey Gimble (3505463)
Matthew Burow (3575111)
Bruce Bunnell (3505469)

August 2015

mRNA expression of ZR75 cells after exposure to leptin knockdown adipose stromal/stem cells (ASCs). ...

Additional file 4: of Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP)

Camille Lehuédé (6241601)
Xia Li (14984)
Stéphanie Dauvillier (6241604)
Charlotte Vaysse (6241607)
Camille Franchet (6241610)
Emily Clement (6241613)
David Esteve (183184)
Mélanie Longué (6241616)
Léonor Chaltiel (6241619)
Sophie Gonidec (6241622)
Ikrame Lazar (6241625)
Aline Geneste (6241628)
Charles Dumontet (193436)
Philippe Valet (231001)
Laurence Nieto (8668)
Frédérique Fallone (6241631)
Catherine Muller (231004)

January 2019

Figure S2. Adipocyte soluble factors reproduce the effect of adipocyte-conditioned medium (AdCM) on ...

Additional file 3: of Selective isolation and characterization of primary cells from normal breast and tumors reveal plasticity of adipose derived stem cells

Annika Weigand (3474701)
Anja Boos (3474713)
Kereshmeh Tasbihi (3474710)
Justus Beier (3474704)
Paul Dalton (3474698)
Michael Schrauder (3474707)
Raymund Horch (3474716)
Matthias Beckmann (3425435)
Pamela Strissel (3474695)
Reiner Strick (189119)

March 2016

Gene expression of invasive and mesenchymal markers in cell isolates. Mammary epithelial cell (MEC),...

Additional file 4: of Utilization of adipocyte-derived lipids and enhanced intracellular trafficking of fatty acids contribute to breast cancer progression

Dejuan Yang (5414129)
Yunhai Li (513276)
Lei Xing (129950)
Yiqing Tan (5414135)
Jiazheng Sun (5414126)
Beilei Zeng (5414132)
Tingxiu Xiang (334805)
Jinxiang Tan (5414138)
Guosheng Ren (334816)
Yuanyuan Wang (20181)

June 2018

Figure S3. (A). Relative mRNA expression levels of FABP4, FABP5 and CD36 in breast cancer cell lines...

Additional file 5: of Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers

Amy Strong (3505457)
Jason Ohlstein (659920)
Brandi Biagas (3575105)
Lyndsay Rhodes (3575099)
Dorothy Pei (3575102)
H. Tucker (3575108)
Claire Llamas (3575096)
Annie Bowles (3505478)
Maria Dutreil (3505475)
Shijia Zhang (497219)
Jeffrey Gimble (3505463)
Matthew Burow (3575111)
Bruce Bunnell (3505469)

August 2015

mRNA expression of T47D cells after exposure to leptin knockdown adipose stromal/stem cells (ASCs). ...

Additional file 8: of Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP)

Camille Lehuédé (6241601)
Xia Li (14984)
Stéphanie Dauvillier (6241604)
Charlotte Vaysse (6241607)
Camille Franchet (6241610)
Emily Clement (6241613)
David Esteve (183184)
Mélanie Longué (6241616)
Léonor Chaltiel (6241619)
Sophie Gonidec (6241622)
Ikrame Lazar (6241625)
Aline Geneste (6241628)
Charles Dumontet (193436)
Philippe Valet (231001)
Laurence Nieto (8668)
Frédérique Fallone (6241631)
Catherine Muller (231004)

January 2019

Figure S6. Hematoxylin/eosin staining of the tumor used to represent major vault protein (MVP) expre...

Additional file 7: of Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers

Amy Strong (3505457)
Jason Ohlstein (659920)
Brandi Biagas (3575105)
Lyndsay Rhodes (3575099)
Dorothy Pei (3575102)
H. Tucker (3575108)
Claire Llamas (3575096)
Annie Bowles (3505478)
Maria Dutreil (3505475)
Shijia Zhang (497219)
Jeffrey Gimble (3505463)
Matthew Burow (3575111)
Bruce Bunnell (3505469)

August 2015

Adipose stromal/stem (ASCs) cells isolated from obese women ( obASCs ) enhance metastasis of breast ...

Additional file 2: of RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3

Yi Niu (456782)
Ziyou Lin (6525587)
Arabella Wan (6525590)
Honglei Chen (125181)
Heng Liang (813618)
Lei Sun (45752)
Yuan Wang (14955)
Xi Li (19208)
Xiao-feng Xiong (5467394)
Bo Wei (188204)
Xiaobin Wu (6525596)
Guohui Wan (6525599)

March 2019

Figure S1. Gene expression in breast cancer. a Volcano plot of gene expression changes in the transc...

Additional file 4: Figure S3. of Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment

Minako Sakurai (4126699)
Yasuhiro Miki (368958)
Kiyoshi Takagi (4126696)
Takashi Suzuki (8491)
Takanori Ishida (822205)
Noriaki Ohuchi (360735)
Hironobu Sasano (368960)

June 2017

Detection of strong S100A7 expressions at the invasive front of MCF7 by interaction with ASCs, showi...

Additional file 6: Figure S5. of Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment

Minako Sakurai (4126699)
Yasuhiro Miki (368958)
Kiyoshi Takagi (4126696)
Takashi Suzuki (8491)
Takanori Ishida (822205)
Noriaki Ohuchi (360735)
Hironobu Sasano (368960)

June 2017

Web-based Kaplan-Meier analysis of S100A7 expression among patients with breast cancer, illustrating...

Additional file 1: of Adipocyte-derived IL-6 and leptin promote breast Cancer metastasis via upregulation of Lysyl Hydroxylase-2 expression

Jin-Yong He (6100892)
Xiao-Hui Wei (6100895)
Si-Jing Li (6100898)
Yang Liu (4829)
Hao-Lin Hu (6100901)
Zheng-Zheng Li (1637104)
Xin-Hong Kuang (6100904)
Lai Wang (23747)
Xin Shi (139139)
Sheng-Tao Yuan (6100907)
Li Sun (4624)

December 2018

Table S1. Sequences of the primers used to detect gene expression by qRT-PCR. Table S2. Characteriza...

Additional file 2: of Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP)

Camille Lehuédé (6241601)
Xia Li (14984)
Stéphanie Dauvillier (6241604)
Charlotte Vaysse (6241607)
Camille Franchet (6241610)
Emily Clement (6241613)
David Esteve (183184)
Mélanie Longué (6241616)
Léonor Chaltiel (6241619)
Sophie Gonidec (6241622)
Ikrame Lazar (6241625)
Aline Geneste (6241628)
Charles Dumontet (193436)
Philippe Valet (231001)
Laurence Nieto (8668)
Frédérique Fallone (6241631)
Catherine Muller (231004)

January 2019

Table S1. Clinical characteristics of the patients with breast cancer and histopathological characte...

Additional file 2: of Adipocyte-derived IL-6 and leptin promote breast Cancer metastasis via upregulation of Lysyl Hydroxylase-2 expression

Jin-Yong He (6100892)
Xiao-Hui Wei (6100895)
Si-Jing Li (6100898)
Yang Liu (4829)
Hao-Lin Hu (6100901)
Zheng-Zheng Li (1637104)
Xin-Hong Kuang (6100904)
Lai Wang (23747)
Xin Shi (139139)
Sheng-Tao Yuan (6100907)
Li Sun (4624)

December 2018

Figure S1. Collagen and PLOD2 expression were significantly increased following coculture with adipo...

Additional file 6: of Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP)

Camille Lehuédé (6241601)
Xia Li (14984)
Stéphanie Dauvillier (6241604)
Charlotte Vaysse (6241607)
Camille Franchet (6241610)
Emily Clement (6241613)
David Esteve (183184)
Mélanie Longué (6241616)
Léonor Chaltiel (6241619)
Sophie Gonidec (6241622)
Ikrame Lazar (6241625)
Aline Geneste (6241628)
Charles Dumontet (193436)
Philippe Valet (231001)
Laurence Nieto (8668)
Frédérique Fallone (6241631)
Catherine Muller (231004)

January 2019

Figure S4. Validation of the two additional small interfering RNAs (siRNAs) targeting major vault pr...

Rachel Sabol (6438179)
Annie Bowles (3505478)
Alex Côté (6727181)
Rachel Wise (6727184)
Benjamen O’Donnell (6727187)
Margarite Matossian (6040496)
Fokhrul Hossain (6040487)
Hope Burks (6438176)
Luis Valle (6727190)
Lucio Miele (81383)
Bridgette Collins-Burow (444016)
Matthew Burow (3575111)
Bruce Bunnell (3505469)

May 2019

Figure S1. Secreted factors from adipose stem cells promotes proliferation and migration of breast c...

Additional file 4: of Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers

Amy Strong (3505457)
Jason Ohlstein (659920)
Brandi Biagas (3575105)
Lyndsay Rhodes (3575099)
Dorothy Pei (3575102)
H. Tucker (3575108)
Claire Llamas (3575096)
Annie Bowles (3505478)
Maria Dutreil (3505475)
Shijia Zhang (497219)
Jeffrey Gimble (3505463)
Matthew Burow (3575111)
Bruce Bunnell (3505469)

August 2015

mRNA expression of ZR75 cells after exposure to leptin knockdown adipose stromal/stem cells (ASCs). ...

Additional file 4: of Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP)

Camille Lehuédé (6241601)
Xia Li (14984)
Stéphanie Dauvillier (6241604)
Charlotte Vaysse (6241607)
Camille Franchet (6241610)
Emily Clement (6241613)
David Esteve (183184)
Mélanie Longué (6241616)
Léonor Chaltiel (6241619)
Sophie Gonidec (6241622)
Ikrame Lazar (6241625)
Aline Geneste (6241628)
Charles Dumontet (193436)
Philippe Valet (231001)
Laurence Nieto (8668)
Frédérique Fallone (6241631)
Catherine Muller (231004)

January 2019

Figure S2. Adipocyte soluble factors reproduce the effect of adipocyte-conditioned medium (AdCM) on ...

Additional file 3: of Selective isolation and characterization of primary cells from normal breast and tumors reveal plasticity of adipose derived stem cells

Annika Weigand (3474701)
Anja Boos (3474713)
Kereshmeh Tasbihi (3474710)
Justus Beier (3474704)
Paul Dalton (3474698)
Michael Schrauder (3474707)
Raymund Horch (3474716)
Matthias Beckmann (3425435)
Pamela Strissel (3474695)
Reiner Strick (189119)

March 2016

Gene expression of invasive and mesenchymal markers in cell isolates. Mammary epithelial cell (MEC),...

Additional file 4: of Utilization of adipocyte-derived lipids and enhanced intracellular trafficking of fatty acids contribute to breast cancer progression

Dejuan Yang (5414129)
Yunhai Li (513276)
Lei Xing (129950)
Yiqing Tan (5414135)
Jiazheng Sun (5414126)
Beilei Zeng (5414132)
Tingxiu Xiang (334805)
Jinxiang Tan (5414138)
Guosheng Ren (334816)
Yuanyuan Wang (20181)

June 2018

Figure S3. (A). Relative mRNA expression levels of FABP4, FABP5 and CD36 in breast cancer cell lines...

Additional file 5: of Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers

Amy Strong (3505457)
Jason Ohlstein (659920)
Brandi Biagas (3575105)
Lyndsay Rhodes (3575099)
Dorothy Pei (3575102)
H. Tucker (3575108)
Claire Llamas (3575096)
Annie Bowles (3505478)
Maria Dutreil (3505475)
Shijia Zhang (497219)
Jeffrey Gimble (3505463)
Matthew Burow (3575111)
Bruce Bunnell (3505469)

August 2015

mRNA expression of T47D cells after exposure to leptin knockdown adipose stromal/stem cells (ASCs). ...

Additional file 8: of Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP)

Camille Lehuédé (6241601)
Xia Li (14984)
Stéphanie Dauvillier (6241604)
Charlotte Vaysse (6241607)
Camille Franchet (6241610)
Emily Clement (6241613)
David Esteve (183184)
Mélanie Longué (6241616)
Léonor Chaltiel (6241619)
Sophie Gonidec (6241622)
Ikrame Lazar (6241625)
Aline Geneste (6241628)
Charles Dumontet (193436)
Philippe Valet (231001)
Laurence Nieto (8668)
Frédérique Fallone (6241631)
Catherine Muller (231004)

January 2019

Figure S6. Hematoxylin/eosin staining of the tumor used to represent major vault protein (MVP) expre...

Additional file 7: of Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers

Amy Strong (3505457)
Jason Ohlstein (659920)
Brandi Biagas (3575105)
Lyndsay Rhodes (3575099)
Dorothy Pei (3575102)
H. Tucker (3575108)
Claire Llamas (3575096)
Annie Bowles (3505478)
Maria Dutreil (3505475)
Shijia Zhang (497219)
Jeffrey Gimble (3505463)
Matthew Burow (3575111)
Bruce Bunnell (3505469)

August 2015

Adipose stromal/stem (ASCs) cells isolated from obese women ( obASCs ) enhance metastasis of breast ...

Additional file 2: of RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3

Yi Niu (456782)
Ziyou Lin (6525587)
Arabella Wan (6525590)
Honglei Chen (125181)
Heng Liang (813618)
Lei Sun (45752)
Yuan Wang (14955)
Xi Li (19208)
Xiao-feng Xiong (5467394)
Bo Wei (188204)
Xiaobin Wu (6525596)
Guohui Wan (6525599)

March 2019

Figure S1. Gene expression in breast cancer. a Volcano plot of gene expression changes in the transc...

Additional file 1: of Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment

Abstract

Extracted data

Additional file 1: of Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment

Abstract

Extracted data

Related items

Related items