Histological images of joint-associated tissue from CHIKV-infected animals at 7 dpi.
- Rebecca Broeckel (834948)
- Julie M. Fox (4116901)
- Nicole Haese (750092)
- Craig N. Kreklywich (190032)
- Soila Sukulpovi-Petty (4116889)
- Alfred Legasse (257296)
- Patricia P. Smith (374431)
- Michael Denton (5120)
- Carsten Corvey (4116886)
- Shiv Krishnan (4116904)
- Lois M. A. Colgin (3826954)
- Rebecca M. Ducore (3826957)
- Anne D. Lewis (4116898)
- Michael K. Axthelm (359276)
- Marie Mandron (4116892)
- Pierre Cortez (697576)
- Jonathan Rothblatt (4116907)
- Ercole Rao (4116910)
- Ingo Focken (2241982)
- Kara Carter (328650)
- Gopal Sapparapau (4116895)
- James E. Crowe Jr. (113691)
- Michael S. Diamond (106070)
- Daniel N. Streblow (190071)
Publication date
June 2017
DOIAbstract
<p>At 7 dpi, joint-associated tissue from the wrist and finger of each animal were fixed, paraffin embedded, sectioned, and stained with hematoxylin and eosin. Shown are representative images of stained sections from joint-associated soft tissue of four animals treated with control antibody SVIR002 or CHIKV mAb SVIR001. In the SVIR002 treated animals, there was abundant inflammation surrounding multiple vessels. In the SVIR001 treated animals (5 or 15 mg/kg dose), there was limited or no perivascular inflammation.</p
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