Aggregated results of simulation Experiment B.

<p>This shows the performance of the three different methods (MELD, t+TFCER, and t-test) using three metrics (MCC,TPR, and PPV) for each of 500 simulations. Violin plots in A and B demonstrate the distributions of results for MCC and TPR respectively. The width of the colored section indicates the density of points. MELD has a greater density of values with high MCC and TPR than either of the two other methods. The colored lines connecting the points indicate results from the same simulation; lines are colored based on the method for which they had the highest value. Gray lines indicate equal values. The paucity of red lines between MELD and t+TFCE reflects very low number of simulations for which t+TFCE performed better than MELD. The distribution of PPV (C) was divided almost entirely between 0 and 1, resulting in a misleading violin plot, so instead we have just plotted a point for each simulation result. The width over which points are spread is indicative of the number of points present at that value. PPV is undefined when a method fails to identify any features as containing signal, so we were unable to connect points across simulations.