<p>(<b>A</b>) Representative hepatic tissue sections of <i>F8</i><sup><i>+/y</i></sup> (WT) vs <i>F8</i><sup><i>-/y</i></sup> mice stained with anti-human VWF antibody (100x and 400x magnification). (<b>B</b>) Visual scoring of the VWF stained hepatic tissue sections of <i>F8</i><sup><i>+/y</i></sup> (WT) vs <i>F8</i><sup><i>-/y</i></sup> mice (n = 7,6). (<b>C</b>) Hepatic VWF transcript levels in <i>F8</i><sup><i>+/y</i></sup> (WT) vs <i>F8</i><sup><i>-/y</i></sup> mice (n = 4,7). All data were expressed as means ± SEM. Statistical comparisons were performed using the Student’s <i>t</i>-test, ** p<0.01.</p
<p>A129 mice were challenged with double the minimum lethal dose of CCHFv, 14 days after booster vac...
<div><p>Von Willebrand factor (VWF) is the carrier protein of the anti-haemophilic Factor VIII (FVII...
<p>(A) A liver section was stained with ORO (frozen section) in SFD- and HFD-fed mice. (B) Red-stain...
<p>Circulating vWF expression is higher in all groups of HF compared to wildtype mice (A). Sectional...
<p>(A) Histopathological analysis of hepatic tissue sections with hematoxylin and eosin staining fro...
<p>(A) Representative fluorescence micrographs of <i>en face</i> immunostaining. Endothelium of the ...
<p>Representative vascular staining pictures of WT (A&B), W/Wv (C&D), and W41/W42 (E&F) myocardium. ...
<p>In liver sections from FVIII-KO mice staining of both rFVIII (A and C, green) and rFVIIIFc (B and...
<p>Sections from FVIII/VWF-DKO mice lacking both VWF and FVIII, show strong punctate vesicular stain...
<p>Tissue sections from control and infected animals were stained with H&E (panels A and E), a modif...
<p>(A) Mouse livers of different dietary groups and mouse strains were HE stained to show intracellu...
<p>(A) Weight of liver, liver triglyceride (TG) content and weight of the gall bladder in WT (<i>n</...
<p>Images are from wildtype (A-C), early HF (D-I), acute HF (J-L), and chronic HF (M-O) mice. vWF st...
<p>(A-C) Quantitation of the radioactivity remaining in perfused organs for <sup>125</sup>I-rFVIII a...
<p>(A) Photographs showing SIRT1(+)-, HIF-1α (+)- and VEGF (+)-spots in joint sections of vehicle co...
<p>A129 mice were challenged with double the minimum lethal dose of CCHFv, 14 days after booster vac...
<div><p>Von Willebrand factor (VWF) is the carrier protein of the anti-haemophilic Factor VIII (FVII...
<p>(A) A liver section was stained with ORO (frozen section) in SFD- and HFD-fed mice. (B) Red-stain...
<p>Circulating vWF expression is higher in all groups of HF compared to wildtype mice (A). Sectional...
<p>(A) Histopathological analysis of hepatic tissue sections with hematoxylin and eosin staining fro...
<p>(A) Representative fluorescence micrographs of <i>en face</i> immunostaining. Endothelium of the ...
<p>Representative vascular staining pictures of WT (A&B), W/Wv (C&D), and W41/W42 (E&F) myocardium. ...
<p>In liver sections from FVIII-KO mice staining of both rFVIII (A and C, green) and rFVIIIFc (B and...
<p>Sections from FVIII/VWF-DKO mice lacking both VWF and FVIII, show strong punctate vesicular stain...
<p>Tissue sections from control and infected animals were stained with H&E (panels A and E), a modif...
<p>(A) Mouse livers of different dietary groups and mouse strains were HE stained to show intracellu...
<p>(A) Weight of liver, liver triglyceride (TG) content and weight of the gall bladder in WT (<i>n</...
<p>Images are from wildtype (A-C), early HF (D-I), acute HF (J-L), and chronic HF (M-O) mice. vWF st...
<p>(A-C) Quantitation of the radioactivity remaining in perfused organs for <sup>125</sup>I-rFVIII a...
<p>(A) Photographs showing SIRT1(+)-, HIF-1α (+)- and VEGF (+)-spots in joint sections of vehicle co...
<p>A129 mice were challenged with double the minimum lethal dose of CCHFv, 14 days after booster vac...
<div><p>Von Willebrand factor (VWF) is the carrier protein of the anti-haemophilic Factor VIII (FVII...
<p>(A) A liver section was stained with ORO (frozen section) in SFD- and HFD-fed mice. (B) Red-stain...