<p>(A) Chain of 20 causal genes. (B) Chain of 10 causal genes. The nodes in purple are genes found by both Hotnet2 and Conflux. The nodes in cyan were only found by Hotnet2. The nodes in red and pink are respectively nodes detected (marginal ≥ 0.2) or having suggestive evidence (marginal ≥ 0.05) by Conflux. Nodes colored in plum were found by Hotnet2 but only have suggestive evidence in Conflux. The diamond shaped nodes are the true causal genes. The sample size used is <i>n</i> = 800.</p
<p>Key driver genes were denoted as larger nodes in the network. Genes were colored based on their m...
Cancers exhibit extensive mutational heterogeneity and the resulting long tail phenomenon complicate...
<p>(A) Disease-gene network showing the relationships of 1,086 genes corresponding to 23 MeSH Headin...
<p>A) <i>KRAS</i> centered star B) <i>GATA3</i> centered star. The nodes in purple are genes found b...
<p>The genes are depicted as <i>nodes</i> of causal network. The hypotheses genes are distinctly col...
Discovering genetic mechanisms driving complex diseases is a hard problem. Existing methods often la...
<p>We generated networks with 3,776 genes. The largest gene network contained 2,717 genes. Genes (no...
<p>Network edges displayed in green and red indicate positive and negative hazard ratios, respective...
<p>The two networks display 38 of the 130 genes in the genetic risk model that are linked to Alzheim...
<p>The network consists of three types of genes, cellular HSC genes (yellow), secreted HSC gene prod...
<p>The genes registered in DisGeNET and experimentally confirmed for the diseases, are shown with co...
Cancers exhibit extensive mutational heterogeneity, and the resulting long-tail phenomenon complicat...
Cancers exhibit extensive mutational heterogeneity, and the resulting long-tail phenomenon complicat...
<p>The columns represent increasing complexity of simulated diseases: 10, 20 and 50 causal genes res...
(A) The global highly correlated genes with FERMT2 identified by the Spearman test in CRC. Red and g...
<p>Key driver genes were denoted as larger nodes in the network. Genes were colored based on their m...
Cancers exhibit extensive mutational heterogeneity and the resulting long tail phenomenon complicate...
<p>(A) Disease-gene network showing the relationships of 1,086 genes corresponding to 23 MeSH Headin...
<p>A) <i>KRAS</i> centered star B) <i>GATA3</i> centered star. The nodes in purple are genes found b...
<p>The genes are depicted as <i>nodes</i> of causal network. The hypotheses genes are distinctly col...
Discovering genetic mechanisms driving complex diseases is a hard problem. Existing methods often la...
<p>We generated networks with 3,776 genes. The largest gene network contained 2,717 genes. Genes (no...
<p>Network edges displayed in green and red indicate positive and negative hazard ratios, respective...
<p>The two networks display 38 of the 130 genes in the genetic risk model that are linked to Alzheim...
<p>The network consists of three types of genes, cellular HSC genes (yellow), secreted HSC gene prod...
<p>The genes registered in DisGeNET and experimentally confirmed for the diseases, are shown with co...
Cancers exhibit extensive mutational heterogeneity, and the resulting long-tail phenomenon complicat...
Cancers exhibit extensive mutational heterogeneity, and the resulting long-tail phenomenon complicat...
<p>The columns represent increasing complexity of simulated diseases: 10, 20 and 50 causal genes res...
(A) The global highly correlated genes with FERMT2 identified by the Spearman test in CRC. Red and g...
<p>Key driver genes were denoted as larger nodes in the network. Genes were colored based on their m...
Cancers exhibit extensive mutational heterogeneity and the resulting long tail phenomenon complicate...
<p>(A) Disease-gene network showing the relationships of 1,086 genes corresponding to 23 MeSH Headin...