<p><b>(A)</b> Representative calbindin-stained cerebellar primary fissure images from untreated wild type, untreated B05 and treated B05 mice. <b>(B)</b> Molecular layer thickness, a measure of calbindin-positive Purkinje dendritic length, in treated and untreated wild type and B05 cerebellum. <b>(C)</b> Representative ATXN1-stained cerebellar primary fissure images from untreated control transgenic (A02), untreated B05 and treated B05 mice. <b>(D)</b> Purkinje nuclei counts in treated and untreated A02 and B05 cerebellum. Error bars represent means ± SEM. Two-way ANOVA,* P < 0.05, ** P < 0.01.</p
<p><b>(A)</b> Representative dendritic whole-cell patch clamp recordings from a fifteen week old wil...
<p><b>(A)</b> Representative traces from Purkinje neurons at five weeks of age where dendritic calci...
<p>Sagittal sections through the medial cerebellum of adult wild type (A, D), <i>Apoer2</i> (B, E) o...
<p><b>(A)</b> Representative images at the cerebellar primary fissure in wild-type mice, ATXN1[82Q] ...
<p>A,B) Representative Z-stacked image of a Purkinje cell as analyzed with Imaris 7.1.1 software, af...
<p>(A) Immunohistochemical staining of cerebellar Purkinje cells with anti-calbindin antibody at var...
<p>(A) Mosaic reconstruction of a representative parasagittal section of the cerebellar vermis in an...
<p>Calbindin-positive (green) Purkinje cells and nuclear stain (blue) of the cell-rich granule cell ...
<p>Fluorescence microscopy analysis for the DARPP-32 (a,b) and calbindin (c,d) proteins highlighting...
<p>A) Double-immunofluorescence staining with calbindin (green) and ataxin-3 (clone 1H9, red) reveal...
<p>(A) Western blots of myelin-specific proteins from brainstem, cerebral cortex and cerebellar homo...
<p><b>(A)</b> Step-length, measured by the footprint runway assay during week 2 of treatment, in wil...
<p><b>A.</b> Cerebella of 3-month-old mice stained with calbindin antibody, specific for Purkinje ne...
<p>Representative microphotograph of the cerebellar lobe (A) with arrow indicating Purkinje cell und...
<p><b>A)</b> Kluver-Barrera's stain was performed on <i>ts3</i> and WT cerebella. Number and morphol...
<p><b>(A)</b> Representative dendritic whole-cell patch clamp recordings from a fifteen week old wil...
<p><b>(A)</b> Representative traces from Purkinje neurons at five weeks of age where dendritic calci...
<p>Sagittal sections through the medial cerebellum of adult wild type (A, D), <i>Apoer2</i> (B, E) o...
<p><b>(A)</b> Representative images at the cerebellar primary fissure in wild-type mice, ATXN1[82Q] ...
<p>A,B) Representative Z-stacked image of a Purkinje cell as analyzed with Imaris 7.1.1 software, af...
<p>(A) Immunohistochemical staining of cerebellar Purkinje cells with anti-calbindin antibody at var...
<p>(A) Mosaic reconstruction of a representative parasagittal section of the cerebellar vermis in an...
<p>Calbindin-positive (green) Purkinje cells and nuclear stain (blue) of the cell-rich granule cell ...
<p>Fluorescence microscopy analysis for the DARPP-32 (a,b) and calbindin (c,d) proteins highlighting...
<p>A) Double-immunofluorescence staining with calbindin (green) and ataxin-3 (clone 1H9, red) reveal...
<p>(A) Western blots of myelin-specific proteins from brainstem, cerebral cortex and cerebellar homo...
<p><b>(A)</b> Step-length, measured by the footprint runway assay during week 2 of treatment, in wil...
<p><b>A.</b> Cerebella of 3-month-old mice stained with calbindin antibody, specific for Purkinje ne...
<p>Representative microphotograph of the cerebellar lobe (A) with arrow indicating Purkinje cell und...
<p><b>A)</b> Kluver-Barrera's stain was performed on <i>ts3</i> and WT cerebella. Number and morphol...
<p><b>(A)</b> Representative dendritic whole-cell patch clamp recordings from a fifteen week old wil...
<p><b>(A)</b> Representative traces from Purkinje neurons at five weeks of age where dendritic calci...
<p>Sagittal sections through the medial cerebellum of adult wild type (A, D), <i>Apoer2</i> (B, E) o...