Outline of the animal experiments.

<p>(A) Experiment 1. The mice were divided into three groups (control, C59, and GG groups; <i>n</i> = 6 per group) and administered 0.2 ml of PBS (control) or LAB suspensions (C59 and GG groups) for 2 weeks. (B) Experiment 2. The mice were divided into seven groups (control, GG-10^7, GG-10^8, GG-10^9, C59-10^7, C59-10^8, and C59-10^9 groups; <i>n</i> = 6 per group per experiment) and was performed in duplicate (round-1 and round-2). Round 2 (n = 3 per group) started a week after the start of the round 1 (n = 3 per group).