Strain and Inoculation Route Dependent Pathogenicity of SB and DOG4 in Mice.

<p>Six- to eight-week-old mice were inoculated i.m. or i.v. with 10⁶ ffu of SB or DOG4. (A) The graph depicts the weight curves of ten mice per group as group averages (mean±standard error). Percentages relate to the body weight at the day of inoculation. (B) Kaplan-Meier plots show the survival probability per day for each experimental group. Data are combined from two independent experiments. Survival curves were statistically different (p<0.0001) between SB i.m. (n = 16) and DOG4 i.m. (n = 17), SB i.v. (n = 18) and DOG4 i.v. (n = 17) as well as between DOG4 i.m. and DOG4 i.v.