<p>Only the tryptophan residue of each peptide (with 6-chloro group shown in green for M011) and amino acids forming the Mdm2 Trp pocket are depicted. M06: orange, blue; M011: cyan, magenta. Corresponding Mdm2 residues for each peptide are in the same colour. Image generated using structures 4UMN and 5XXK.</p
<p>(A) Human MD-2 (pdb id 3FXI, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pon...
Superposition of the rainbow-colored structure of St I (A) [5] and St II (B) [4], with the black-col...
<p>Left: Simulations (see Materials and Methods) indicate packing interactions between M62 (yellow) ...
<p>(A) <i>β</i>-sheet monomer, (B) <i>β</i>-sheet tetramer. The peptide is shown in cartoon and colo...
<p>(<b>A</b>) superpositions of MIP-MDM2 fusion (PDB ID = 2RUH), DI:MDM2 (3G03), PMI:MDM2 (3EQS), an...
<p>MOMP-derived peptide docking to I-Ab MCH II. Cartoon representations of the docked poses of four ...
<div><p>(A) Overall structure of the HAUSP TRAF-like domain bound to MDM2 peptide is shown in a ribb...
<p>(<b>A, left</b>) Superpositioning of backbone heavy atoms of the 20 MIP-MDM2 three-dimensional st...
<div><p>(A) MDM2 peptide (red) binds to the same surface groove as the p53 peptide (magenta). Residu...
<p>(A) Domain structure, NetPhos predicted phosphorylation sites, cysteine residues and disulphide b...
<p>MHC class II (I-Ab)-bound <i>C</i>. <i>trachomatis</i> peptides are highlighted in yellow.</p
<p>The 2Fo-Fc electron density map, which has been contoured at 1.2 σ, clearly demonstrates the pres...
<p>(<b>A</b>) A network of hydrogen bonding and hydrophobic interactions formed by the phosphorylate...
<p>(A), (B) and (C): superposition of LCMV (pink) with PV (blue) structures, with the peptide in sti...
In the middle is the structure of the IMI compound surrounded by four peptides YSM21, PSM22, PSW31, ...
<p>(A) Human MD-2 (pdb id 3FXI, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pon...
Superposition of the rainbow-colored structure of St I (A) [5] and St II (B) [4], with the black-col...
<p>Left: Simulations (see Materials and Methods) indicate packing interactions between M62 (yellow) ...
<p>(A) <i>β</i>-sheet monomer, (B) <i>β</i>-sheet tetramer. The peptide is shown in cartoon and colo...
<p>(<b>A</b>) superpositions of MIP-MDM2 fusion (PDB ID = 2RUH), DI:MDM2 (3G03), PMI:MDM2 (3EQS), an...
<p>MOMP-derived peptide docking to I-Ab MCH II. Cartoon representations of the docked poses of four ...
<div><p>(A) Overall structure of the HAUSP TRAF-like domain bound to MDM2 peptide is shown in a ribb...
<p>(<b>A, left</b>) Superpositioning of backbone heavy atoms of the 20 MIP-MDM2 three-dimensional st...
<div><p>(A) MDM2 peptide (red) binds to the same surface groove as the p53 peptide (magenta). Residu...
<p>(A) Domain structure, NetPhos predicted phosphorylation sites, cysteine residues and disulphide b...
<p>MHC class II (I-Ab)-bound <i>C</i>. <i>trachomatis</i> peptides are highlighted in yellow.</p
<p>The 2Fo-Fc electron density map, which has been contoured at 1.2 σ, clearly demonstrates the pres...
<p>(<b>A</b>) A network of hydrogen bonding and hydrophobic interactions formed by the phosphorylate...
<p>(A), (B) and (C): superposition of LCMV (pink) with PV (blue) structures, with the peptide in sti...
In the middle is the structure of the IMI compound surrounded by four peptides YSM21, PSM22, PSW31, ...
<p>(A) Human MD-2 (pdb id 3FXI, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pon...
Superposition of the rainbow-colored structure of St I (A) [5] and St II (B) [4], with the black-col...
<p>Left: Simulations (see Materials and Methods) indicate packing interactions between M62 (yellow) ...