<i>SREBP</i> is a candidate host factor during early midgut infection.

<p>(A) <i>SREBP</i> expression levels measured by RNA-Seq (log₂-transformed normalized counts) on day 1 and day 4 post DENV exposure in the midgut of control (n = 6) and DENV-infected (n = 16) individuals. <i>P</i>-values of the pairwise t-tests are indicated. (B) Correlation of <i>SREBP</i> expression level measured by RNA-Seq (log₂-transformed normalized counts) and viral RNA load (log₁₀ RNA copies / midgut) in DENV-infected midguts on day 1 and day 4 post virus exposure. Black lines represent the linear regression and light orange shaded areas represent the 95% confidence intervals. Pearson's coefficients of determination (r) and <i>P</i>-values of the linear regression coefficient are indicated.