Progressive increase in airway inflammation and remodeling after acute HDM exposure in inbred C57BL/6 mice.

<p>Representative images of proximal airways showing inflamed lung areas (left) (scale bar: 0.5 mm), and airway thickness (orange bars in insets) (center left), mucus-producing cells per epithelium length (red arrowheads in insets) (center right) and collagen content (right) (scale bars: 50 μm) in PBS- or HDM-treated C57BL/6 mice at D3, D5 and D7. Bottom graphs represent quantification of the abovementioned parameters. Data are expressed as mean ± SEM (n = 4 animals per group). **<i>p</i><0.01; ***<i>p</i><0.001 (Dunn-Sidak multiple comparison test). H&E, Hematoxilin and eosin; PAS, Periodic Acid Schiff; AW, airway; HDM, house dust mite; PBS, phosphate buffered saline.