Relative expression of liver selenoprotein transcripts significantly altered by Se deficiency in both B6 mice and Founder mice.

<p>Shown are expression levels for <i>Selenop</i>, <i>Gpx1</i>, <i>Selenow</i>, <i>Selenoh</i>, <i>Txnrd2</i>, <i>Txnrd3</i>, and <i>Gpx4</i>, expressed relative to the level in +Se B6 mice. Expression is shown as a percentage of levels in Se-adequate B6 mice. Left portion of each panel shows the relative activity in B6 mice fed 0 μg Se/g (-Se) and 0.2 μg Se/g (+Se) relative to +Se B6 mice; values are mean ± SEM (n = 3/treatment). Right portion of each panel shows the relative levels in -Se and +Se Founder mice as box-and-whisker plots, where the box delineates 25 to 75%, the bar in the box the median, and the error bars 10 and 90%; also shown are individual values linked by lines for each of the 8 strains. Means with asterisks are significantly different from Se-adequate values (P<0.05).