Log-transformed P-values of association tests determined by logistic regression analysis with penetrance for genotype with the lowest risk of 0.01 and odds ratio increments of 0.2. The sample size was 1000 for both cases and controls. The penetrance for the genotype with the lowest risk was 0.01, and the odds ratio (r) ranged from 1.1 to 2.0 in increments of 0.2. Red and black circles/lines indicate values for risk allele frequencies shown in red and black, respectively. (TIFF 570 kb
<p>Allelic components of the presented haplotypes are rs3787138, rs1044396 and rs3787140 SNPs, respe...
Figure S2. Association of the insulin genetic score with potential confounders. Association of 18-SN...
a<p>Major/minor alleles;</p>b<p>Minor homozygote/Heterozygote/Major homozygote;</p>c<p>Minor allele ...
Risk allele frequencies of LD block SNVs for 213 diseases extracted from the VARIMED database of Eur...
Statistical power analysis for myopia study [18]. The number of cases was 190, and the number of con...
Statistical power analysis for schizophrenia study [21]. The number of cases was 5001, and the numbe...
BACKGROUND:Genome-wide association studies (GWASs) have revealed relationships between over 57,000 g...
1<p>minor allele2</p><p>minor allele frequency.</p>3<p>p-value corrected with Bonferroni correction....
∧<p>One sample did not amplify when this marker was tested.</p>*<p>risk allele, odds ratios are calc...
*<p>Abbreviations and definitions are given in <a href="http://www.plosone.org/article/info:doi/10.1...
<p>The upper panel indicates the alternative alleles in different grey shades, and the defined ~167 ...
<p>The risk alleles considered are the variant alleles of rs7574865, rs3099844 and rs3024505 SNPs.</...
<p>Notes. *Risk alleles in the haplotypes are labeled by bold. **MAF: minor allele frequency.</p
<p>Each box denotes the odds ratio (OR) comparing the corresponding Matteoni types on the horizontal...
<p>Allele load (0,1,2) refers to the number of risk alleles: <i>677T</i> for <i>MTHFR C677T</i> and ...
<p>Allelic components of the presented haplotypes are rs3787138, rs1044396 and rs3787140 SNPs, respe...
Figure S2. Association of the insulin genetic score with potential confounders. Association of 18-SN...
a<p>Major/minor alleles;</p>b<p>Minor homozygote/Heterozygote/Major homozygote;</p>c<p>Minor allele ...
Risk allele frequencies of LD block SNVs for 213 diseases extracted from the VARIMED database of Eur...
Statistical power analysis for myopia study [18]. The number of cases was 190, and the number of con...
Statistical power analysis for schizophrenia study [21]. The number of cases was 5001, and the numbe...
BACKGROUND:Genome-wide association studies (GWASs) have revealed relationships between over 57,000 g...
1<p>minor allele2</p><p>minor allele frequency.</p>3<p>p-value corrected with Bonferroni correction....
∧<p>One sample did not amplify when this marker was tested.</p>*<p>risk allele, odds ratios are calc...
*<p>Abbreviations and definitions are given in <a href="http://www.plosone.org/article/info:doi/10.1...
<p>The upper panel indicates the alternative alleles in different grey shades, and the defined ~167 ...
<p>The risk alleles considered are the variant alleles of rs7574865, rs3099844 and rs3024505 SNPs.</...
<p>Notes. *Risk alleles in the haplotypes are labeled by bold. **MAF: minor allele frequency.</p
<p>Each box denotes the odds ratio (OR) comparing the corresponding Matteoni types on the horizontal...
<p>Allele load (0,1,2) refers to the number of risk alleles: <i>677T</i> for <i>MTHFR C677T</i> and ...
<p>Allelic components of the presented haplotypes are rs3787138, rs1044396 and rs3787140 SNPs, respe...
Figure S2. Association of the insulin genetic score with potential confounders. Association of 18-SN...
a<p>Major/minor alleles;</p>b<p>Minor homozygote/Heterozygote/Major homozygote;</p>c<p>Minor allele ...