Cardoon is a crop well adapted to Mediterranean climatic conditions that is able to grow also in marginal lands thus reducing competition for land with food crops. It is considered a key crop for bio-refinery since it allows producing different interesting molecules for industrial application. From stems it is possible to obtain large amounts of cellulose, grains are a good source of oil and proteins and roots can be a source of inulin. The aim of this research has been to evaluate the productive levels of different genotypes of cardoon in two different climatic conditions of Mediterranean cropland (a site in the Vesuvius plain and a site in the internal hilly cropland). In both the sites, during 3 years (from 2012-2013 to 2014-2015), ...