The effcient indexing of large and sparse N-gram datasets is crucial in several applications in Information Retrieval, Natural Language Processing and Machine Learning. Because of the stringent efficiency requirements, dealing with billions of N-grams poses the challenge of introducing a compressed representation that preserves the query processing speed. In this paperwe study the problem of reducing the space required by the representation of such datasets, maintaining the capability of looking up for a given N-gram within micro seconds. For this purpose we describe compressed, exact and lossless data structures that achieve, at the same time, high space reductions and no time degradation with respect to state-of-The-Art software packages....