Dual-drug-loaded pH-responsive fiber scaffolds were successfully prepared by coaxial electrospinning. These were designed with the aim of being sutured into the resection site after tumor removal, to aid recovery and prevent cancer recurrence. The shell was made up of a mixture of gelatin and sodium bicarbonate (added to provide pH-sensitivity), and was loaded with the anti-inflammatory drug ciprofloxacin; the core comprised poly(lactide-co-ε-caprolactone) with the chemotherapeutic doxorubicin hydrochloride. Scanning electron microscopy revealed most fibers were smooth and homogeneous. Transmission electron microscopy demonstrated the presence of a clear core/shell structure. The fiber scaffolds were further characterized using infrared spe...
Controlled and efficient delivery of therapeutics to tumor cells is one of the key issues in cancer ...
In the clinical management of solid tumors, the possibility to successfully couple the regeneration ...
Coaxial electrospinning is a technique that allows the production of nanofibers with a core–shell st...
A coaxial nanofibrous scaffold of poly (ε-caprolactone) and gelatin/cellulose acetate encapsulating ...
Electrospinning was used to prepare core/shell fibers containing the active pharmaceutical ingredien...
Encapsulation of a model anti-cancer drug, 5-Fluorouracul (5-FU) into biocompatible core-shell nanof...
In this work, we report new formulations for the combined photo-chemotherapy of colon cancer. Fibers...
In this work, we aimed to develop new materials to reduce the secondary injuries which can be impart...
© 2018 Wiley Periodicals, Inc. Electrospinning (ES) of gelatin often requires cytotoxic organic solv...
Coaxial and triaxial electrospinning are novel methods for fabrication of multilayered nano and micr...
Design and development of smart nano-sized delivery devices for controlled drug release in response ...
© BME-PT. In this work we present the drug release properties and morphological studies of fibers fo...
A multifunctional, dual-drug carrier platform was successfully constructed. Core-shell structured Na...
CO2 infusion of biomolecules is a benign, green, and inexpensive method to provide much-needed bioch...
Nanocarriers have attracted broad attention in cancer therapy because of their ability to carry drug...
Controlled and efficient delivery of therapeutics to tumor cells is one of the key issues in cancer ...
In the clinical management of solid tumors, the possibility to successfully couple the regeneration ...
Coaxial electrospinning is a technique that allows the production of nanofibers with a core–shell st...
A coaxial nanofibrous scaffold of poly (ε-caprolactone) and gelatin/cellulose acetate encapsulating ...
Electrospinning was used to prepare core/shell fibers containing the active pharmaceutical ingredien...
Encapsulation of a model anti-cancer drug, 5-Fluorouracul (5-FU) into biocompatible core-shell nanof...
In this work, we report new formulations for the combined photo-chemotherapy of colon cancer. Fibers...
In this work, we aimed to develop new materials to reduce the secondary injuries which can be impart...
© 2018 Wiley Periodicals, Inc. Electrospinning (ES) of gelatin often requires cytotoxic organic solv...
Coaxial and triaxial electrospinning are novel methods for fabrication of multilayered nano and micr...
Design and development of smart nano-sized delivery devices for controlled drug release in response ...
© BME-PT. In this work we present the drug release properties and morphological studies of fibers fo...
A multifunctional, dual-drug carrier platform was successfully constructed. Core-shell structured Na...
CO2 infusion of biomolecules is a benign, green, and inexpensive method to provide much-needed bioch...
Nanocarriers have attracted broad attention in cancer therapy because of their ability to carry drug...
Controlled and efficient delivery of therapeutics to tumor cells is one of the key issues in cancer ...
In the clinical management of solid tumors, the possibility to successfully couple the regeneration ...
Coaxial electrospinning is a technique that allows the production of nanofibers with a core–shell st...