OGD triggered Zn2+ rises and Ca2+ deregulation events in CA1 and CA3 hippocampal pyramidal neurons of MT-III and ZnT3 knockout mice.

OGD induces delayed neuronal death of mature hippocampal neurons in culture.

Joana Fernandes (587970)
Marta Vieira (587971)
Laura Carreto (34863)
Manuel A. S. Santos (34864)
Carlos B. Duarte (103288)
Ana Luísa Carvalho (372324)
Armanda E. Santos (587972)

June 2014

(A) OGD causes hippocampal neuronal cell death, as determined by analysis of nuclear morph...

ZnT3 expression levels are down-regulated in the brain of Mcoln1 knockout mice

Jonathan Chacon
Lauren Rosas
Math P. Cuajungco

March 2019

Abstract Aim Zinc is a critical divalent cation in mammalian brain, but its concentration must be st...

Generation of CA3 pyramidal neuron-selective NMDA receptor knockout mice.

Fumiaki Fukushima (375106)
Kazuhito Nakao (375129)
Toru Shinoe (375131)
Masahiro Fukaya (47739)
Shin-ichi Muramatsu (115935)
Kenji Sakimura (47744)
Hirotaka Kataoka (375109)
Hisashi Mori (47743)
Masahiko Watanabe (47746)
Toshiya Manabe (375132)
Masayoshi Mishina (47748)

February 2013

A–C, X-ray film autoradiography for GluRζ1 mRNAs. Arrowheads indicate the CA3 region. D–F,...

OGD triggered Zn2+ rises and Ca2+ deregulation events in CA1 and CA3 hippocampal pyramidal neurons of MT-III and ZnT3 knockout mice.

Medvedeva, Yuliya V. (5240395)
Ji, Sung G. (5240386)
Yin, Hong Z. (5240392)
Weiss, John H. (5240389)

May 2018

The posted data provide the control characterization of the oxygen glucose deprivation (OGD) trig...

Differential Vulnerability of CA1 versus CA3 Pyramidal Neurons After Ischemia: Possible Relationship to Sources of Zn2+ Accumulation and Its Entry into and Prolonged Effects on Mitochondria.

Medvedeva, Yuliya V
Ji, Sung G
Yin, Hong Z
Weiss, John H

January 2017

Excitotoxic mechanisms contribute to the degeneration of hippocampal pyramidal neurons after recurre...

Differential Vulnerability of CA1 versus CA3 Pyramidal Neurons After Ischemia: Possible Relationship to Sources of Zn2+ Accumulation and Its Entry into and Prolonged Effects on Mitochondria.

Medvedeva, Yuliya V
Ji, Sung G
Yin, Hong Z
Weiss, John H

January 2017

Excitotoxic mechanisms contribute to the degeneration of hippocampal pyramidal neurons after recurre...

Intracellular Zn2+ accumulation contributes to synaptic failure, mitochondrial depolarization, and cell death in an acute slice oxygen-glucose deprivation model of ischemia

Lin, B
Shuttleworth, CW
Medvedeva, YV
Weiss, JH

January 2009

Despite considerable evidence for contributions of both Zn2+ and Ca2+ in ischemic brain damage, the ...

δPKC activation following OGD decreases Bad phosphorylation via PP2A activation.

Kunjan R. Dave (348112)
Sanjoy K. Bhattacharya (158939)
Isabel Saul (348113)
R. Anthony DeFazio (238180)
Cameron Dezfulian (348114)
Hung Wen Lin (348115)
Ami P. Raval (348116)
Miguel A. Perez-Pinzon (348117)

February 2013

A) Immunoblot of p-Bad in hippocampal synaptosomes subjected to oxygen glucose deprivation (OGD) ...

Zn2+ entry through the mitochondrial calcium uniporter is a critical contributor to mitochondrial dysfunction and neurodegeneration.

Ji, Sung
Medvedeva, Yuliya
Weiss, John

March 2020

Excitotoxic Ca2+ accumulation contributes to ischemic neurodegeneration, and Ca2+ can enter the mito...

Zn2+ entry through the mitochondrial calcium uniporter is a critical contributor to mitochondrial dysfunction and neurodegeneration.

Ji, Sung G
Medvedeva, Yuliya V
Weiss, John H

March 2020

Excitotoxic Ca2+ accumulation contributes to ischemic neurodegeneration, and Ca2+ can enter the mito...

Energy deprivation transiently enhances rhythmic inhibitory events in the CA3 hippocampal network in vitro.

Gee, C. E.
Benquet, Pascal
Demont-Guignard, Sophie
Wendling, Fabrice
Gerber, U.

July 2010

CE. GEE and P. Benquet : These authors contributed equally to this study.International audienceOxyge...

δPKC translocates to the mitochondria following CA and δPKC activation following OGD increases cytochrome c release.

Kunjan R. Dave (348112)
Sanjoy K. Bhattacharya (158939)
Isabel Saul (348113)
R. Anthony DeFazio (238180)
Cameron Dezfulian (348114)
Hung Wen Lin (348115)
Ami P. Raval (348116)
Miguel A. Perez-Pinzon (348117)

February 2013

A) Immunoblot of δPKC in hippocampal mitochondria of a rat subjected to 8 min of CA and 1 h of re...

Zn2+ entry through the mitochondrial calcium uniporter is a critical contributor to mitochondrial dysfunction and neurodegeneration.

Ji, Sung G
Medvedeva, Yuliya V
Weiss, John H

March 2020

Excitotoxic Ca2+ accumulation contributes to ischemic neurodegeneration, and Ca2+ can enter the mito...

Intramitochondrial Zn2+ accumulation via the Ca2+ uniporter contributes to acute ischemic neurodegeneration

Medvedeva, Yuliya V
Weiss, John H

August 2014

Ca(2+) and Zn(2+) have both been implicated in the induction of acute ischemic neurodegeneration. We...

Preconditioning of cortical neurons by oxygen-glucose deprivation: tolerance induction through abbreviated neurotoxic signaling: Am J Physiol Cell Physiol

Tauskela, Joseph
Brunette, Eric
Monette, R.
Comas, Tanya
Morley, P.

October 2003

Transient exposure of rat cortical cultures to nonlethal oxygen-glucose deprivation (OGD preconditio...

OGD induces delayed neuronal death of mature hippocampal neurons in culture.

Joana Fernandes (587970)
Marta Vieira (587971)
Laura Carreto (34863)
Manuel A. S. Santos (34864)
Carlos B. Duarte (103288)
Ana Luísa Carvalho (372324)
Armanda E. Santos (587972)

June 2014

(A) OGD causes hippocampal neuronal cell death, as determined by analysis of nuclear morph...

ZnT3 expression levels are down-regulated in the brain of Mcoln1 knockout mice

Jonathan Chacon
Lauren Rosas
Math P. Cuajungco

March 2019

Abstract Aim Zinc is a critical divalent cation in mammalian brain, but its concentration must be st...

Generation of CA3 pyramidal neuron-selective NMDA receptor knockout mice.

Fumiaki Fukushima (375106)
Kazuhito Nakao (375129)
Toru Shinoe (375131)
Masahiro Fukaya (47739)
Shin-ichi Muramatsu (115935)
Kenji Sakimura (47744)
Hirotaka Kataoka (375109)
Hisashi Mori (47743)
Masahiko Watanabe (47746)
Toshiya Manabe (375132)
Masayoshi Mishina (47748)

February 2013

A–C, X-ray film autoradiography for GluRζ1 mRNAs. Arrowheads indicate the CA3 region. D–F,...

OGD triggered Zn2+ rises and Ca2+ deregulation events in CA1 and CA3 hippocampal pyramidal neurons of MT-III and ZnT3 knockout mice.

Medvedeva, Yuliya V. (5240395)
Ji, Sung G. (5240386)
Yin, Hong Z. (5240392)
Weiss, John H. (5240389)

May 2018

The posted data provide the control characterization of the oxygen glucose deprivation (OGD) trig...

Differential Vulnerability of CA1 versus CA3 Pyramidal Neurons After Ischemia: Possible Relationship to Sources of Zn2+ Accumulation and Its Entry into and Prolonged Effects on Mitochondria.

Medvedeva, Yuliya V
Ji, Sung G
Yin, Hong Z
Weiss, John H

January 2017

Excitotoxic mechanisms contribute to the degeneration of hippocampal pyramidal neurons after recurre...

Differential Vulnerability of CA1 versus CA3 Pyramidal Neurons After Ischemia: Possible Relationship to Sources of Zn2+ Accumulation and Its Entry into and Prolonged Effects on Mitochondria.

Medvedeva, Yuliya V
Ji, Sung G
Yin, Hong Z
Weiss, John H

January 2017

Excitotoxic mechanisms contribute to the degeneration of hippocampal pyramidal neurons after recurre...

Intracellular Zn2+ accumulation contributes to synaptic failure, mitochondrial depolarization, and cell death in an acute slice oxygen-glucose deprivation model of ischemia

Lin, B
Shuttleworth, CW
Medvedeva, YV
Weiss, JH

January 2009

Despite considerable evidence for contributions of both Zn2+ and Ca2+ in ischemic brain damage, the ...

δPKC activation following OGD decreases Bad phosphorylation via PP2A activation.

Kunjan R. Dave (348112)
Sanjoy K. Bhattacharya (158939)
Isabel Saul (348113)
R. Anthony DeFazio (238180)
Cameron Dezfulian (348114)
Hung Wen Lin (348115)
Ami P. Raval (348116)
Miguel A. Perez-Pinzon (348117)

February 2013

A) Immunoblot of p-Bad in hippocampal synaptosomes subjected to oxygen glucose deprivation (OGD) ...

Zn2+ entry through the mitochondrial calcium uniporter is a critical contributor to mitochondrial dysfunction and neurodegeneration.

Ji, Sung
Medvedeva, Yuliya
Weiss, John

March 2020

Excitotoxic Ca2+ accumulation contributes to ischemic neurodegeneration, and Ca2+ can enter the mito...

Zn2+ entry through the mitochondrial calcium uniporter is a critical contributor to mitochondrial dysfunction and neurodegeneration.

Ji, Sung G
Medvedeva, Yuliya V
Weiss, John H

March 2020

Excitotoxic Ca2+ accumulation contributes to ischemic neurodegeneration, and Ca2+ can enter the mito...

Energy deprivation transiently enhances rhythmic inhibitory events in the CA3 hippocampal network in vitro.

Gee, C. E.
Benquet, Pascal
Demont-Guignard, Sophie
Wendling, Fabrice
Gerber, U.

July 2010

CE. GEE and P. Benquet : These authors contributed equally to this study.International audienceOxyge...

δPKC translocates to the mitochondria following CA and δPKC activation following OGD increases cytochrome c release.

Kunjan R. Dave (348112)
Sanjoy K. Bhattacharya (158939)
Isabel Saul (348113)
R. Anthony DeFazio (238180)
Cameron Dezfulian (348114)
Hung Wen Lin (348115)
Ami P. Raval (348116)
Miguel A. Perez-Pinzon (348117)

February 2013

A) Immunoblot of δPKC in hippocampal mitochondria of a rat subjected to 8 min of CA and 1 h of re...

Zn2+ entry through the mitochondrial calcium uniporter is a critical contributor to mitochondrial dysfunction and neurodegeneration.

Ji, Sung G
Medvedeva, Yuliya V
Weiss, John H

March 2020

Excitotoxic Ca2+ accumulation contributes to ischemic neurodegeneration, and Ca2+ can enter the mito...

Intramitochondrial Zn2+ accumulation via the Ca2+ uniporter contributes to acute ischemic neurodegeneration

Medvedeva, Yuliya V
Weiss, John H

August 2014

Ca(2+) and Zn(2+) have both been implicated in the induction of acute ischemic neurodegeneration. We...

Preconditioning of cortical neurons by oxygen-glucose deprivation: tolerance induction through abbreviated neurotoxic signaling: Am J Physiol Cell Physiol

Tauskela, Joseph
Brunette, Eric
Monette, R.
Comas, Tanya
Morley, P.

October 2003

Transient exposure of rat cortical cultures to nonlethal oxygen-glucose deprivation (OGD preconditio...

OGD induces delayed neuronal death of mature hippocampal neurons in culture.

Joana Fernandes (587970)
Marta Vieira (587971)
Laura Carreto (34863)
Manuel A. S. Santos (34864)
Carlos B. Duarte (103288)
Ana Luísa Carvalho (372324)
Armanda E. Santos (587972)

June 2014

(A) OGD causes hippocampal neuronal cell death, as determined by analysis of nuclear morph...

ZnT3 expression levels are down-regulated in the brain of Mcoln1 knockout mice

Jonathan Chacon
Lauren Rosas
Math P. Cuajungco

March 2019

Abstract Aim Zinc is a critical divalent cation in mammalian brain, but its concentration must be st...

Generation of CA3 pyramidal neuron-selective NMDA receptor knockout mice.

Fumiaki Fukushima (375106)
Kazuhito Nakao (375129)
Toru Shinoe (375131)
Masahiro Fukaya (47739)
Shin-ichi Muramatsu (115935)
Kenji Sakimura (47744)
Hirotaka Kataoka (375109)
Hisashi Mori (47743)
Masahiko Watanabe (47746)
Toshiya Manabe (375132)
Masayoshi Mishina (47748)

February 2013

A–C, X-ray film autoradiography for GluRζ1 mRNAs. Arrowheads indicate the CA3 region. D–F,...

OGD triggered Zn2+ rises and Ca2+ deregulation events in CA1 and CA3 hippocampal pyramidal neurons of MT-III and ZnT3 knockout mice.

Abstract

Extracted data

OGD triggered Zn2+ rises and Ca2+ deregulation events in CA1 and CA3 hippocampal pyramidal neurons of MT-III and ZnT3 knockout mice.

Abstract

Extracted data

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