Histochemical studies on the cerebral cortex of epileptics. Part 2. On succinic dehydrogenase in the cerebral cortex of epileptics.

The specimen was taken in the same way as part 1, stained by WACHSTEIN et MEISEL method and the activity of succinic dehydrogenase in the nerve cells was histochemically investigated. 1) In idopathic epileptics the activity of succinic dehydrogenase in nerve cells in premotor area of the cerebral cortex increased, but that in those, which had provocated convulsion with metrazol before the operation, showed a some decrease. 2) In symptomatic epileptics it showed no increasing. From the above mentioned it is confirmed that the nerve cells in the cerebral cortex of the symptomatic epileptics are not so hypersensitive, and on the contrary those of idiopathic epileptics, in which no organic changes are found, are hypersensitive i.e are in convulsive arrangement