Effects of Formalin on the Activity of Antibodies

Effects of formalin on the activity of antibodies were studied by means of precipitin reactions, hemagglutination with sensitized blood cells, and paper electrophoresis. No precipitin reaction occurred in the area of high concentrations of formalin, while no marked changes in reaction were observed in the area of low concentrations compared to control tests. Almost same results were noticed in hemagglutination tests with sensitized blood cells as in the case of precipitin tests. On paper electrophoresis significant changes were noticed where one per-cent formalin was used as experimental reagent, while the same results were observed in 0.001 per-cent formalin as in control tests