Fat Prospects for Healing Cutaneous Wounds: New Activities Under the Sheets Diabetes 2015;64:2717–2719 | DOI: 10.2337/db15-0533

results for dermal wound healing in full-thickness skin defects in Zucker diabetic fatty (ZDF) rats. The team fabricated and applied transplanted living cell sheets com-prising allogeneic adipose-derived stem cells (ASCs) har-vested from the inguinal fat pads of normal rats. They attempt to address the current challenges with abnormal wound healing in increasing numbers of patients with diabetes who present with difficult cutaneous wound healing problems (2,3). This deficiency is often clinically characterized by persistent inflammation, hypergranula-tion, excessive tissue bed exudates, and chronic inability to resolve, resulting in enhanced bacterial burdens, in-fections, ulcerations, and more serious complications. Delayed cutaneous healing in these patients is attributed to combinations of predisposing factors associated wit