Animal Experiments with Adrenal Cortical Extracts*!

SINCE the extraction of a potent principle from the adrenal cortex by Swingle and Pfiffner19 and by Hartmann8 much greater interest has centered upon this gland than ever before. Animal experimentation has at last acquired a tool to work with, and it is being used extensively. Great hopes have been entertained for the successful treatment of Addison's dis-ease, and the cortical extract has been used for this purpose with some de-gree of success by Rowntree and others.10 The very nature of this con-dition, however, would preclude the possibility of a cure, since it is caused in most cases by a progressive, de