Cohort study High-sensitivity troponin useful for diagnosis and prognosis in patients with acute coronary syndrome

High-sensitivity cardiac troponin (hs-cTnT) determin-ation has improved cTnT evaluation in patients with acute coronary syndrome (ACS). The hs-cTnT ‘normal value ’ is considered to be <99th percentile (0.014 ug/l). Hs-cTnT can diagnose an acute myocardial infarction (AMI) earlier than common cTnT determinations, even in patients with previous CAD.1 2 Some studies have shown higher specificity of hs-cTnT in AMI diagnosis, compared with common cTnT determinations.3 Hs-cTnT is also a better predictor of death and heart failure in patients with chest pain and ACS during follow-up.1 2 4 Methods The APACE study, a multicentre prospective trial, enrolled a total of 1181 consecutive patients who were admitted to the emergency department because of ches