Chronic pulmonary infections with Pseudomonas aeruginosa are a debilitating component of the genetic disease cystic fibrosis (CF). The persistence of these infections is partly due to iron uptake as this contributes to bacterial growth and the formation of resilient biofilms. In conditions of restricted availability, iron can be sequestered by the endogenous siderophores pyoverdine and pyochelin and may also be acquired as haem through the Has and Phu pathways. This research primarily sought to ascertain the use and relative importance of the pyoverdine, pyochelin, Has and Phu systems in iron acquisition in CF. Further objectives were to elucidate how the lung environment affects iron uptake, to characterise regulatory components of the Has...
Iron availability is critical to many bacteria and increased iron has been described in airway secr...
Iron availability is critical to many bacteria and increased iron has been described in airway secr...
Iron availability is critical to many bacteria and increased iron has been described in airway secr...
Chronic pulmonary infections with Pseudomonas aeruginosa are a debilitating component of the genetic...
Chronic pulmonary infections with Pseudomonas aeruginosa are a debilitating component of the genetic...
Pseudomonas aeruginosa chronically infects the lungs of more than 80% of adult patients with cystic ...
Pseudomonas aeruginosa chronically infects the lungs of more than 80 % of adult patients with cystic...
The lungs of patients with cystic fibrosis become chronically infected with the bacterium Pseudomona...
The bacterium Pseudomonas aeruginosa is commonly isolated from the general environment and also infe...
ABSTRACT Chronic, biofilm-like infections by the opportunistic pathogen Pseudomonas aeruginosa are a...
Reid DW, Anderson GJ, Lamont IL. Role of lung iron in determining the bacterial and host struggle in...
Iron availability is critical to many bacteria and increased iron has been described in airway secre...
Pseudomonas aeruginosa is the main cause of lung function decline among cystic fibrosis (CF) patient...
Pseudomonas aeruginosa is a leading cause of hospital-acquired pneumonia and chronic lung infections...
Pseudomonas aeruginosa is a leading cause of hospital-acquired pneumonia and chronic lung infections...
Iron availability is critical to many bacteria and increased iron has been described in airway secr...
Iron availability is critical to many bacteria and increased iron has been described in airway secr...
Iron availability is critical to many bacteria and increased iron has been described in airway secr...
Chronic pulmonary infections with Pseudomonas aeruginosa are a debilitating component of the genetic...
Chronic pulmonary infections with Pseudomonas aeruginosa are a debilitating component of the genetic...
Pseudomonas aeruginosa chronically infects the lungs of more than 80% of adult patients with cystic ...
Pseudomonas aeruginosa chronically infects the lungs of more than 80 % of adult patients with cystic...
The lungs of patients with cystic fibrosis become chronically infected with the bacterium Pseudomona...
The bacterium Pseudomonas aeruginosa is commonly isolated from the general environment and also infe...
ABSTRACT Chronic, biofilm-like infections by the opportunistic pathogen Pseudomonas aeruginosa are a...
Reid DW, Anderson GJ, Lamont IL. Role of lung iron in determining the bacterial and host struggle in...
Iron availability is critical to many bacteria and increased iron has been described in airway secre...
Pseudomonas aeruginosa is the main cause of lung function decline among cystic fibrosis (CF) patient...
Pseudomonas aeruginosa is a leading cause of hospital-acquired pneumonia and chronic lung infections...
Pseudomonas aeruginosa is a leading cause of hospital-acquired pneumonia and chronic lung infections...
Iron availability is critical to many bacteria and increased iron has been described in airway secr...
Iron availability is critical to many bacteria and increased iron has been described in airway secr...
Iron availability is critical to many bacteria and increased iron has been described in airway secr...