Background: The roles of the Hedgehog (Hh) pathway in controlling vertebrate retinal development have been studied extensively; however, species- and context-dependent findings have provided differing conclusions. Hh signaling has been shown to control both population size and cell cycle kinetics of proliferating retinal progenitors, and to modulate differentiation within the retina by regulating the timing of cell cycle exit. While cell cycle exit has in turn been shown to control cell fate decisions within the retina, a direct role for the Hh pathway in retinal cell fate decisions has yet to be established in vivo. Results: To gain further insight into Hh pathway function in the retina, we have analyzed retinal development in leprechaun/p...
Contains fulltext : 88522.pdf (publisher's version ) (Open Access)BACKGROUND: The ...
Summary: Upon injury, Müller glia cells of the zebrafish retina reprogram themselves to progenitor c...
BACKGROUND: Aberrant activation of the Hedgehog (Hh) signaling pathway in different organisms has sh...
The roles of the Hedgehog (Hh) pathway in controlling vertebrate retinal development have been studi...
Jonathan Bibliowicz and Jeffery M. Gross are with the Section of Molecular Cell and Developmental Bi...
During embryonic development, the Hedgehog (Hh) signaling pathway plays an important role in the gro...
AbstractHedgehog (Hh) signaling is required for eye development in vertebrates; known roles in the z...
In contrast to mammals, zebrafish are capable of regenerating retinal neurons. Essential to regenera...
Zebrafish continuously add new rod photoreceptors to their retinas as a consequence of persistent bo...
Unlike most vertebrates, zebrafish possess the unique ability to regenerate organ tissues and retina...
The secreted Hedgehog (Hh) molecule acts as a morphogen, mitogen, and cell survival factor during em...
Use (A,B). At 72 hpf, mutants exhibit an eye phenotype where the pigmented epithelium is extended in...
The secreted Hedgehog (Hh) molecule acts as a morphogen, mitogen, and cell survival factor during em...
Background: The genetic cascades underpinning vertebrate early eye morphogenesis are poorly understo...
In the anterior vertebrate head, a population of neural crest cells (NCCs) migrates to the periocula...
Contains fulltext : 88522.pdf (publisher's version ) (Open Access)BACKGROUND: The ...
Summary: Upon injury, Müller glia cells of the zebrafish retina reprogram themselves to progenitor c...
BACKGROUND: Aberrant activation of the Hedgehog (Hh) signaling pathway in different organisms has sh...
The roles of the Hedgehog (Hh) pathway in controlling vertebrate retinal development have been studi...
Jonathan Bibliowicz and Jeffery M. Gross are with the Section of Molecular Cell and Developmental Bi...
During embryonic development, the Hedgehog (Hh) signaling pathway plays an important role in the gro...
AbstractHedgehog (Hh) signaling is required for eye development in vertebrates; known roles in the z...
In contrast to mammals, zebrafish are capable of regenerating retinal neurons. Essential to regenera...
Zebrafish continuously add new rod photoreceptors to their retinas as a consequence of persistent bo...
Unlike most vertebrates, zebrafish possess the unique ability to regenerate organ tissues and retina...
The secreted Hedgehog (Hh) molecule acts as a morphogen, mitogen, and cell survival factor during em...
Use (A,B). At 72 hpf, mutants exhibit an eye phenotype where the pigmented epithelium is extended in...
The secreted Hedgehog (Hh) molecule acts as a morphogen, mitogen, and cell survival factor during em...
Background: The genetic cascades underpinning vertebrate early eye morphogenesis are poorly understo...
In the anterior vertebrate head, a population of neural crest cells (NCCs) migrates to the periocula...
Contains fulltext : 88522.pdf (publisher's version ) (Open Access)BACKGROUND: The ...
Summary: Upon injury, Müller glia cells of the zebrafish retina reprogram themselves to progenitor c...
BACKGROUND: Aberrant activation of the Hedgehog (Hh) signaling pathway in different organisms has sh...