RESEARCH a o e

Full list of author information is available at the end of the articleIn spite of many measurements, malaria remains a big public health problem where it is estimated that about a million deaths and over 400 million malaria cases occur worldwide each year, with 90 % of these deaths occurring in sub-Saharan Africa [1]. Owing to the spread of Plasmo-dium falciparum resistant strains in the majority of mala-ria endemic countries, the World Health Organization (WHO) recommended artemisinin-based combination therapy (ACT) for the treatment of uncomplicated P. fal-ciparum malaria, which is adopted in most of the African panded its recommendations to include laboratory con-firmation with microscopy or a rapid diagnostic test (RDT) before initiating anti-malarial therapy [3]. Hence, the management of fever in African countries underwent a radical change in the recent years from the presumptiv