Full list of author information is available at the end of the articleZambia has demonstrated considerable success in scaling-up recommended malaria control interventions over the past decade and shown corresponding reductions in mal-aria morbidity and mortality [1]. Following these successes, the recent National Malaria Strategic Plan called for ambi-tious efforts to work toward malaria elimination and the es-tablishment of at least five malaria free zones by 2015 [2]. in conjunction with the Malaria Control and Elimination Partnership in Africa (MACEPA) implemented a mass malaria testing and treatment (MTAT) intervention with artemether-lumefantrine (AL)(Coartem®) (MTAT-AL) in Southern Province, Zambia. The MTAT-AL intervention aimed to r...