A new method for the determination of serum nucleotidase

This paper deals with comparative studies on the levels of alkaline phosphatase, the presence of bone phosphatase as measured electro-phoretically, and levels of S'-nucleotidase, as measured in the presence of phenylphosphate in sera of patients suffering from bone me-tastases. Secondly, the levels of 5'-nucleotidase and other serum enzymes were studied in cancer patients during various kinds of therapy. A classification of serum enzymes is proposed, based on their preferential response to either liver metastases or toxic liver injury or both. Es wird über vergleichende Untersuchungen der Aktivität der alkalischen Phosphatase, das Vorkommen von Knochenphosphatase durch elektrophoretischen Nachweis und der Aktivität der S'-Nucleotidase, bestimmt in Gegenwart von Phenylphosphat, im Serum von Pa-tienten mit Knochenmetastasen berichtet