Editorial Adiponectin and myocardial infarction: a paradox or a paradigm?

This editorial refers to ‘Adiponectin is an independent predictor of all-cause mortality, cardiac mortality, and myocardial infarction in patients presenting with chest pain’ † by E. Cavusoglu et al., on page 2300 Once considered a disease of the affluent, obesity now pre-vails in the poorer developing nations as well.1 Although it is widely acknowledged that obesity, together with its allied metabolic disorders, is closely associated with the patho-genesis of cardiovascular diseases (CVDs),1,2 the precise molecular links between obesity and CVD remain speculat-ive. It is evident that adipose tissue, traditionally viewed as a passive energy reservoir, plays a role in homeostasis and metabolism. Adipose tissue has autocrine, paracrine, and endocrine functions and synthesizes and releases a wide array of cytokine-like products collectively termed adi