The routine study of bone marrow trephine biopsies involves fixation, decalcification, paraffin-embedment, sectioning and staining. However, this process creates artifacts, produces shrinkage of tissue, consumes time and can result in sections of unsatisfactory cytological quality. It also renders the tissue unsuitable for enzyme-histochemical and immunohistochemical analyses. Frozen section of bone marrow without decalcification was evaluated as an alternative method for the study of bone marrow. This method was found to give sections with comparable cytological quality to that of paraffin-embedment, yielded sections for interpretation within 24 hours, and allowed enzyme-histochemical and irnmunohistochemical analyses to be applied success...
Unfortunately, the combination of the superior histologic embedding technique for semi-thin sectioni...
Introduction: Bone marrow examination has become increasingly important for the diagnosis and treatm...
An adequate bone marrow aspirate is essential for a rapid diagnosis of acute leukaemia by multicolou...
Histopathological examination of a bone marrow (BM) trephine biopsy is an integral part of the diagn...
We have systematically investigated a variety of fixation and plastic embedding procedures and arriv...
Cryostat sections from frozen samples of human bone marrow trephine biopsies were used for immunohis...
Specimens of bone marrow trephine biopsy (BMT) are transported and fixed in acetic acid–zinc–formali...
BACKGROUND Given its prognostic value, there is renewed interest in molecular staging in non-Hodgkin...
A recently developed procedure, that has been shown to be suitable for detailed immunohistological a...
In this study of 163 cryopreserved bone marrow (BM) trephine biopsies, immunophenotypes of BM infilt...
Studies have compared the role of bone marrow aspirate cytology and trephine biopsy for diagnosing v...
Comparative evaluation of bone marrow aspirate particle smears, imprints and biopsy sections was don...
Cytological detail is well demonstrated in an improved method of staining aspirated bone marrow sect...
Unexplained cytopenia is one of the most common indications for performing trephine bone marrow (BM)...
Introduction: Bone marrow aspiration (BMA) and trephine biopsy are indispensable diagnostic tools fo...
Unfortunately, the combination of the superior histologic embedding technique for semi-thin sectioni...
Introduction: Bone marrow examination has become increasingly important for the diagnosis and treatm...
An adequate bone marrow aspirate is essential for a rapid diagnosis of acute leukaemia by multicolou...
Histopathological examination of a bone marrow (BM) trephine biopsy is an integral part of the diagn...
We have systematically investigated a variety of fixation and plastic embedding procedures and arriv...
Cryostat sections from frozen samples of human bone marrow trephine biopsies were used for immunohis...
Specimens of bone marrow trephine biopsy (BMT) are transported and fixed in acetic acid–zinc–formali...
BACKGROUND Given its prognostic value, there is renewed interest in molecular staging in non-Hodgkin...
A recently developed procedure, that has been shown to be suitable for detailed immunohistological a...
In this study of 163 cryopreserved bone marrow (BM) trephine biopsies, immunophenotypes of BM infilt...
Studies have compared the role of bone marrow aspirate cytology and trephine biopsy for diagnosing v...
Comparative evaluation of bone marrow aspirate particle smears, imprints and biopsy sections was don...
Cytological detail is well demonstrated in an improved method of staining aspirated bone marrow sect...
Unexplained cytopenia is one of the most common indications for performing trephine bone marrow (BM)...
Introduction: Bone marrow aspiration (BMA) and trephine biopsy are indispensable diagnostic tools fo...
Unfortunately, the combination of the superior histologic embedding technique for semi-thin sectioni...
Introduction: Bone marrow examination has become increasingly important for the diagnosis and treatm...
An adequate bone marrow aspirate is essential for a rapid diagnosis of acute leukaemia by multicolou...