Genomic variation associated with mortality among adults of European and African ancestry with heart failure: The cohorts for heart and aging research in genomic epidemiology consortium
- Morrison, Alanna
- Felix, Janine
- Cupples, Adrienne
- Glazer, Nicole
- Loehr, Laura
- Dehghan, Abbas
- Demissie, Serkalem
- Bis, Joshua
- Rosamond, Wayne
- Aulchenko, Yurii
- Haritunians, Talin
- Folsom, Aaron
- Rivadeneira Ramirez, Fernando
- Benjamin, Emelia
- Lumley, Thomas
- Couper, David
- Stricker, Bruno
- Rice, Kenneth
- Wang, Thomas
- Chang, Patricia
- Hofman, Albert
- Levy, Daniel
- Rotter, Jerome
- Fox, Ervin
- Uitterlinden, André
- Psaty, Bruce
- Willerson, James
- Tikka-Kleemola, Päivi
- Boerwinkle, Eric
- Witteman, Jacqueline
- Vasan, Ramachandran Srini
- Smith, Nicholas
- O'Donnell, Christopher
View in ORKG Publication date
January 2010
DOI Publisher
Ovid Technologies (Wolters Kluwer Health) ISSN
1942-325XAbstract
Background-Prognosis and survival are significant concerns for individuals with heart failure (HF). To better understand the pathophysiology of HF prognosis, the association between 2 366 858 single-nucleotide polymorphisms (SNPs) and all-cause mortality was evaluated among individuals with incident HF from 4 community-based prospective cohorts: the Atherosclerosis Risk in Communities Study, the Cardiovascular Health Study, the Framingham Heart Study, and the Rotterdam Study. Methods and Results-Participants were 2526 individuals of European ancestr