textabstractContext Matrix metalloproteinases (MMPs) are associated with diastolic dysfunction and heart failure in acquired heart disease. Objective To investigate the role of MMPs as novel biomarkers in clinically stable adults with congenital heart disease. Methods We measured serum MMP-2, -3, -9 and tissue inhibitor of matrix metalloproteinase-1 in 425 patients and analysed the association with cardiac function and exercise capacity. Results MMP-2 was significantly associated with exercise capacity, ventilatory efficiency and left ventricular deceleration time, independently of age, sex, body surface area and NT-proBNP. Conclusion MMP-2 may provide new information in the clinical evaluation of adults with congenital heart disease
ObjectivesWe studied the role of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs...
Background: Circulating metalloproteinases (MMP) and their inhibitors (TIMP) are indices of vascular...
During cardiopulmonary-bypass matrix-metalloproteinases released may contribute to ventricular dysfu...
Context Matrix metalloproteinases (MMPs) are associated with diastolic dysfunction and heart failure...
The aim of the present study was to verify whether plasma MMPs (matrix metalloproteinases) and TIMPs...
The aim of the present study was to verify whether plasma MMPs (matrix metalloproteinases) and TIMPs...
Objective: The pathological effects of matrix metalloproteinases and their tissue inhibitors in card...
Matrix metalloproteinases (MMPs) are a family of zinc-dependent proteolytic enzymes that degrade ext...
Heart failure (HF) represents a complex multifactorial syndrome, characterized by crucial structural...
金沢大学大学院医学系研究科 Background: Some patients with hypertrophic cardiomyopathy (HCM) develop left ventricu...
Adverse cardiac remodeling following myocardial infarction (MI) remains a significant cause of conge...
OBJECTIVES: We studied the role of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIM...
Aims: Development of heart failure depends on systemic and molecular abnormalities among which are t...
The aim of the study was to assess MMP-2 (matrix metalloproteinase-2) and TIMP-2 (tissue inhibitor o...
The article is devoted to an important section of the pediatric cardiology — dilated cardiomyopathy ...
ObjectivesWe studied the role of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs...
Background: Circulating metalloproteinases (MMP) and their inhibitors (TIMP) are indices of vascular...
During cardiopulmonary-bypass matrix-metalloproteinases released may contribute to ventricular dysfu...
Context Matrix metalloproteinases (MMPs) are associated with diastolic dysfunction and heart failure...
The aim of the present study was to verify whether plasma MMPs (matrix metalloproteinases) and TIMPs...
The aim of the present study was to verify whether plasma MMPs (matrix metalloproteinases) and TIMPs...
Objective: The pathological effects of matrix metalloproteinases and their tissue inhibitors in card...
Matrix metalloproteinases (MMPs) are a family of zinc-dependent proteolytic enzymes that degrade ext...
Heart failure (HF) represents a complex multifactorial syndrome, characterized by crucial structural...
金沢大学大学院医学系研究科 Background: Some patients with hypertrophic cardiomyopathy (HCM) develop left ventricu...
Adverse cardiac remodeling following myocardial infarction (MI) remains a significant cause of conge...
OBJECTIVES: We studied the role of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIM...
Aims: Development of heart failure depends on systemic and molecular abnormalities among which are t...
The aim of the study was to assess MMP-2 (matrix metalloproteinase-2) and TIMP-2 (tissue inhibitor o...
The article is devoted to an important section of the pediatric cardiology — dilated cardiomyopathy ...
ObjectivesWe studied the role of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs...
Background: Circulating metalloproteinases (MMP) and their inhibitors (TIMP) are indices of vascular...
During cardiopulmonary-bypass matrix-metalloproteinases released may contribute to ventricular dysfu...