AbstractIn all metazoans, the expression of group B HMG domain Sox transcription factors is associated with the earliest stages of CNS development. In Drosophila, SoxNeuro (SoxN) is involved in dorso-ventral patterning of the neuroectoderm, and in the formation and segregation of neuroblasts. In this report, we show that SoxN expression persists in a subset of neurons and glial cells of the ventral nerve cord at embryonic stages 15/16. In an attempt to address SoxN function in late stages of CNS development, we have used a chromatin immunoprecipitation approach to isolate genomic regions bound in vivo by SoxN. We identified several genes involved in the regulation of axon scaffolding as potential direct target genes of SoxN, including beat1...
SummaryHere, we describe the embryonic central nervous system expression of 5,000 GAL4 lines made us...
All multicellular life begins as a single cell—the fertilised egg, from which the adult organism dev...
Group B Sox genes play a critical developmental role in both vertebrates and insects. Within the mod...
AbstractIn all metazoans, the expression of group B HMG domain Sox transcription factors is associat...
BACKGROUND: Sox proteins encompass an evolutionarily conserved family of transcription factors with ...
© 2018, The Author(s). Precise control of neurite guidance during development is essential to ensure...
BACKGROUND: Group B Sox domain transcription factors play conserved roles in the specification and d...
BACKGROUND: Group B Sox domain transcription factors play important roles in metazoan central nervou...
AbstractSox domain proteins encompass a conserved family of transcriptional regulators that are impl...
AbstractNeural crest cells and oligodendrocytes as the myelinating glia of the central nervous syste...
The central nervous system (CNS) is composed of three major cell types, namely neurons, astrocytes ...
The differentiation of stem cells into the more than 100 billion neurons that compose the central ne...
AbstractWe have investigated the expression and function of the Sox15 transcription factor during th...
AbstractAlthough Sox1, Sox2, and Sox3 are all part of the Sox-B1 group of transcriptional regulators...
The SOX proteins belong to the superfamily of transcription factors (TFs) that display properties of...
SummaryHere, we describe the embryonic central nervous system expression of 5,000 GAL4 lines made us...
All multicellular life begins as a single cell—the fertilised egg, from which the adult organism dev...
Group B Sox genes play a critical developmental role in both vertebrates and insects. Within the mod...
AbstractIn all metazoans, the expression of group B HMG domain Sox transcription factors is associat...
BACKGROUND: Sox proteins encompass an evolutionarily conserved family of transcription factors with ...
© 2018, The Author(s). Precise control of neurite guidance during development is essential to ensure...
BACKGROUND: Group B Sox domain transcription factors play conserved roles in the specification and d...
BACKGROUND: Group B Sox domain transcription factors play important roles in metazoan central nervou...
AbstractSox domain proteins encompass a conserved family of transcriptional regulators that are impl...
AbstractNeural crest cells and oligodendrocytes as the myelinating glia of the central nervous syste...
The central nervous system (CNS) is composed of three major cell types, namely neurons, astrocytes ...
The differentiation of stem cells into the more than 100 billion neurons that compose the central ne...
AbstractWe have investigated the expression and function of the Sox15 transcription factor during th...
AbstractAlthough Sox1, Sox2, and Sox3 are all part of the Sox-B1 group of transcriptional regulators...
The SOX proteins belong to the superfamily of transcription factors (TFs) that display properties of...
SummaryHere, we describe the embryonic central nervous system expression of 5,000 GAL4 lines made us...
All multicellular life begins as a single cell—the fertilised egg, from which the adult organism dev...
Group B Sox genes play a critical developmental role in both vertebrates and insects. Within the mod...