Receptor-mediated regulation of constitutive secretion

  • Luini, A
  • DE MATTEIS, Maria Antonietta
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Publication date
January 1993
ISSN
0962-8924

Abstract

The traditional distinction between regulated and constitutive secretion may have contributed to the general belief that the latter is insensitive to extracellular modulatory signals. However, it now appears that signalling from membrane receptors can in fact modulate constitutive membrane traffic. In this article we discuss the molecular mechanisms, as well as the functional significance, of this modulation

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